It is evident from what has been said that to prevent plague our efforts should be directed in two ways:—(1) To prevent the importation of germs; (2) to make the environment of a place such that the germs, even if imported, may not find suitable condition for their growth. To accomplish the first we need (_a_) inspection of people coming from infected places; (_b_) stopping importation of such articles as may carry infection with them; (_c_) quarantine, a word which owes its origin to the fact that, daring the epidemic of plague at Milan in 1527, patients when cured were despatched to lazarettos and detained there 40 days. For the second, we require (_a_) sanitary precautions by guardians of public health; (_b_) observance of rules of personal hygiene by which good health can be maintained. (1). Wherever possible a medical inspection should be made to prevent importation of the disease. This is, however, a very difficult matter, and one unforeseen difficulty was experienced at Sukkur, where it was found that people booked to stations short of Sukkur, and rebooked at stations on the other side. Still this measure is highly important, and should be carried out most rigorously as long as there is any chance of importation of plague into an unaffected country. It is needless to feel the pulse of the patient; his gait, temperature, and look would afford a great deal of information. Information should be obtained from where the patient is travelling. An examination should also be made of clothes. Dirty clothes, soiled linen and rags should not be allowed to pass through an inspection post. (2). There should be a disinfecting or sterilizing room fitted with a steam sterilizer in all large railway stations, where all goods should be disinfected. Mail bags should also be subjected to this disinfection. Transmission of such goods as corpses, used clothes, rags, waste paper, fur, hide, feather, and fish should be entirely suspended. (3). If quarantine is imposed, it should be for a period not less than ten days. Every arrangement, however, should be made for suitable accommodation and sanitation in quarantine camps. In a quarantine camp new arrivals should not be mixed up with those who are already in quarantine. (4). Ships from infected ports should be carefully watched. If any infection is discovered, then isolation of the sick, disinfection of the ship and quarantine are required, but ships with clean bills of health, and if ten days have passed since its departure from the infected port, may be admitted after medical inspection. It must, however, be borne in mind that rats could easily carry infection from one port to another without any fear of detection. These facts show that medical inspection and quarantine may be useful, but they can never be perfect, and therefore the principal safeguard of a place lies in the improvement of its sanitation, and therefore greater attention and energy should be directed towards it.