I remain, Sir, &c. ROBERT LEWINS. P. S.--In one, the pulse had ceased at the wrist eight hours before the injection. Dr. Alison had seen the patient eight hours before the operation, and the pulse was then imperceptible. _Quality Street, Leith, May 29th, 1832, 1 o’clock, A. M._ _Origin of the Cholera at Quebec._ _Board of Health, Quebec, June 25th, 1832._ The undersigned, appointed by the Board of Health to investigate and report upon the introduction and treatment of the cholera, now existing in this country, have agreed to the following Report, which they respectfully submit. The disease, on its first appearance in this city, exhibited all the characters of that commonly called the Asiatic or Spasmodic Cholera. It commenced about the 8th instant, in boarding houses and taverns in the Cul-de-Sac--a low, uncleanly, and ill-ventilated part of the city--crowded with emigrants of the lowest description, with sailors and other persons of irregular habits. About the fourth day of the disease, (the 12th,) it showed itself in the more elevated parts of the city, among the wealthier classes of society, and persons of sober and regular habits, who could have had but little, if any, direct communication with the people among whom the disease had first appeared. About the same date, (the 12th,) the disease was observed in various parts of the city, and in several neighbouring parishes, some few miles distant, having a constant intercourse with it. The cases continued to increase in number until about the 16th or 18th, (being the 8th or 10th day of the disease,) when they began to subside, both in number and in violence--the disease still prevailing more extensively in the ill-ventilated parts of the city above mentioned. About the period of its greatest prevalence, (the 8th or 10th day of the disease,) the number of cases was estimated to be between 250 and 300, in the course of twenty-four hours. The undersigned have not as yet been able to discover that any case of cholera has been landed from any vessel in the harbour, before nor until several days after its first appearance in the city. They deem it necessary to add, that some parishes in the neighbourhood of Quebec have continued free from the disease until lately, and that no case appears to have yet occurred at Three Rivers, an intermediate and populous town between Montreal and Quebec, where the steamboats with emigrants from Quebec, generally arrive. Since the appearance of this malady, only two soldiers have been attacked in Quebec, and those while on duty--the rest being closely confined to their quarters. The symptoms were the most violent at the commencement, and continued so until about the 16th or 18th, when they began to mitigate in severity, as the cases diminished in number.