The first American to comprehend the greatness of the fur-trade on the North-west Coast of the Pacific, both as a means of profit to himself and as a patriotic impulse to direct his own nation into the channels of westward expansion, was John Ledyard. Thomas Jefferson and John Paul Jones became deeply interested in Ledyard's extravagant hopes of future wealth and glory, but all his efforts came to naught, and in 1788 this brilliant adventurer, just on the eve of setting out to explore the interior of Africa, suddenly put an end to his own life at Cairo, Egypt. Ledyard should always be remembered by his countrymen, for, though his glowing visions were unfulfilled, he was an important link in the great chain which bound Oregon to our own country. During these same years, several Englishmen, already noted in the chapter on discovery, Portlock, Dixon, Hanna, Barclay, and Meares, were actively engaged in the fur-trade, while the voyages of La Perouse and Marchand carried the flag of France on the same quest, and Spain's once illustrious emblem of world dominion was borne by Quadra, Valdes, Galiano, Fidalgo, Quimper, Caamano, and several others. While these explorers all were impelled in part by national pride and diplomacy, the hope of sharing the spoils of the sea-otter droves was the chief lure to the tempestuous seas of the North Pacific. In Bullfinch's _Oregon and El Dorado_ is a very interesting narration of the inception of the American part in the fur-trade of Oregon. In a building known as the Coolidge Building in Boston a company were gathered together in 1787 discussing the reports, then first made public, of Cook's voyages. Mr. Joseph Barrell, a rich merchant of Boston, was much impressed with Cook's account of the chances of barter with the Indians for furs and the disposal of them in China for yet more profitable cargoes of teas, silks, and other characteristic commodities of that land. As a result of this conference, a company was formed in Boston to prosecute such enterprise, the members of the company, Messrs. Barrell, Brown, Bulfinch, Darby, Hatch, and Pintard, being among the foremost of the business men in Boston in that good year of the creation of the American Constitution.