Given a cell, it is necessary to keep that cell under favourable conditions. Otherwise the unstable protoplasm breaks up. It must have the elements necessary to keep up its cycle of changes in the proper form, which we may now call food, and many cells have to go and find this requisite. It must keep away from injurious influences, and it must race other cells for localities favourable to its growth and multiplication; in fact, the cell must work. That a cell can, in virtue of its chemical affinities alone, move about, seeking favourable conditions, showing discrimination and doing work, seems incomprehensible. In the first place, how can it move? There is only one way: it must effect a redistribution of its substance, and contrive that those parts of the cell whose activity is applied to this end shall be so situated as to produce definite changes in its shape according to the cause which evokes them. Of the way in which different cells move we shall have a good deal more to say later. Why protoplasm should be influenced to move still requires explanation. Yet the gap between protoplasm and other substances is really not so great, after all. Heat and magnetism cause movement in inanimate matter, and the response of protoplasm as exemplified by some of the minute unicellular animals is almost as mechanical. Some kinds which swim in water move to the positive pole of a galvanic battery, others to the negative, if the wires are dipped into the vessel containing them. Some move towards light, others away from it, with unvarying regularity. Temperature and chemical substances also cause a definite effect upon these micro-organisms. And all these movements are wholly involuntary, absolutely invariable, and, in fact, reactions evoked by fixed causes. Nevertheless, it will be seen that protoplasm can only continue to exist in the form of a cell, since, unless thus organized, it can neither keep itself among favourable surroundings nor prepare fresh ingredients to make good its waste. If a cell be cut up into several pieces, these detached bits of protoplasm will live for a time; but death overtakes them as soon as they have used up their reserve material. When this is gone, they have to consume their own substance, a process which quickly proves fatal. Should a fragment contain a small part of the nucleus cut away with it, it will live a little longer; but it is only the piece which contains the nucleus more or less intact—in other words, the cell, damaged though it be—which can survive and recover from such mutilation.