Thus, if we paid attention, as usual, only to the palpable occurrences which take place on the earth and beneath its surface, the Sweating Sickness of the above-mentioned year might appear to be unconnected with more considerable commotions of organic life. The powers of nature, however, are in their operations too subtle to be comprehended by our dull senses and by the coarse mechanism of our organs; nay, precisely at a time when neither the one nor the other indicate any alteration around us, those operations bring to light the most extraordinary phenomena in the human frame—that most sensitive index of secret influences on life. This observation was fully confirmed at the time of the first return of the sweating fever. For whilst this disease remained confined to England, there appeared in the southern and central parts of Europe a new and fatal epidemic, which thenceforth visited these nations almost continually with intense malignity. This was the petechial fever, a disease unknown to the older physicians, which was first observed in 1490, in Granada, where it threatened to annihilate the army of Ferdinand the Catholic, and made great havoc also among the Saracens[415]. The bubo plague had immediately preceded it, (1483, 1485, 1486, 1488, 1489, and 1490[416],) and it may with no small probability be assumed that the petechial fever had resulted from this as a peculiar variety, since in other countries also, fifteen years later, the bubo plague degenerated in various ways, and examples are not wanting in which particular forms or constituent parts of great epidemics thus branch off from them, in the same manner as, under favourable circumstances, these will combine together, and united into one destructive whole, multiply the sources of danger. Yet some contemporaries were of opinion that the petechial fever had been brought over to Granada[417] by Venetian mercenaries from Cyprus, where they had fought against the Turks, and where this disorder was said to have been indigenous. Notwithstanding some good works[418] already existing, this matter has need of a more thorough examination, which might bring to light important and instructive results, respecting the rise and spread of the petechial fever, and especially respecting its relation to other plagues. Whatever may be held with regard to the true origin of this fever, thus much is established, that it was at first an independent European disease, and that, at the commencement, having occupied the southern part of this quarter of the world, it then became connected, in a manner as extraordinary as it was worthy of observation, with the sweating sickness of the north; since the nearly simultaneous eruption of the sweating fever in England, with the great epidemic petechial fever in the year 1505, may be justly attributed to an influence common to both, although unquestionably of greater power in the latter.