To us in the medical profession it is of no little interest that in Rome, according to Varro, there stood three temples on the Esquiline dedicated to the goddess of Fever and one to Mephitis. Tacitus relates that a temple to Mephitis was the only building left standing after the destruction of Cremona, where there was also an altar dedicated to the Evil Eye. We know, also, that in the very centre of the Forum there stood an altar to Cloacina, the Goddess of Typhoid. What complete sway this goddess has held from ancient times to the present I need scarcely tell you. "When Rome, after the fall of the empire, relapsed into its most insanitary condition this old worship reappeared in another shape, and a chapel arose near the Vatican to the _Madonna della Febre_, the most popular in Rome in times of sickness or epidemic." This simply shows a transfer of ideas, the attributes of Diana being conveyed over to her Christian successor, the virgin, whose cult became equally supreme. The principal symbol of this cult was the horned moon or crescent, and, in consequence, horns in one form or another became the most common of objects as amulets against the Evil Eye. So comprehensive and persistent is this belief in Naples that, in the absence of a horn in some shape, the mere utterance of the name _corno_ was supposed to be an effectual protection. Even more than this, the name _Un Corno_ became applicable to any and every charm or amulet against the Evil Eye. We may find many references to the Horn in Scripture, where it served both as an emblem of dignity and as an amulet. Most curious it is that the phylactery with which the Pharisees adorned their garments, and which called forth the most scathing denunciation by the Master, was undoubtedly an emblem of a horn, and worn as an amulet against the Evil Eye. At the beginning of the Christian era it had become fashionable to wear these, and how they were enlarged and made not only badges of sanctity but marks of worldly honor, we may read in the New Testament.