As the doctors were accustomed to retain their most valuable recipes, and put up the medicines themselves, selling them as nostrums, and because of the heavy percentage demanded by them for those intrusted to the apothecaries, and the small profit accruing from the sale of medicines at the time, the poor wretched "cookes" were necessarily kept in extreme poverty. So, in order to eke out a living, the apothecaries were also grocers and small tradesmen. As at the present day, they were not required to possess any knowledge of medical science beyond the reading of a few books "relating to the nature of plants," hence very little honor or profit could accrue from the business alone. Grocers kept a small stock of drugs, sometimes in a corner by themselves, but not unusually thrown about and jumbled amongst the articles kept for culinary and other purposes. As mineral medicines became more generally used, these were also added to the little stock, and not unfrequently was some poisonous substance dealt out by a green clerk (as is often the case nowadays) to the little errand girl, sent in haste for some culinary article. Allspice and aloes, sugar and tartar emetic, lemon essence and laudanum, were thrown promiscuously together into drawers, or upon the most convenient shelves, and you need not go far into the country to witness the same lamentable spectacle in the enlightened nineteenth century. The apothecary gave the most attention, as now, to the exposition and sale of those articles which sold the most readily, and returned the greatest profit. All druggists at present sell cigars and tobacco, at the same time not unusually posting up a conspicuous sign-- NO SMOKING ALLOWED HERE. The following is a case in point:-- _Druggist._ Smoking not allowed here, sir. _Customer._ Why! I just bought this cigar from you. _Druggist._ Well, we also sell emetics and cathartics. That does not license customers to sit down and enjoy them on the premises. In the thirteenth year of the reign of James I. of England (and James VI. of Scotland) the apothecaries and grocers were disunited. The charter, however, placed the former under the control of the College of Physicians, who were endowed with the arbitrary powers of inspecting their shops and wares, and inflicting punishments for alleged neglects, deficiencies, and malpractices. The physicians knew so little, that the apothecaries soon were enabled to cope with them; "and before a generation had passed away the apothecaries had gained so much, socially and pecuniarily, that the more prosperous of them could afford to laugh in the face of the faculty, and by the commencement of the next century they were fawned upon by the younger physicians, and were in a position to quarrel with the old, which they soon improved."