[Illustration: _The separate chromosomes in a dividing cell are
photographed and then can be identified by their overall length, the
position of the centromere, or point where the two strands join, and
other characteristics. The photomicrograph can then be cut apart and the
chromosomes grouped in a karyotype, which is an arrangement according to
a standard classification to show chromosome complement and
abnormalities. The karotype below is of a normal male, since it shows X
and Y sex chromosomes and 22 pairs of other, autosomal, chromosomes. By
contrast, the cells in the upper pictures are abnormal, with only 45
chromosomes each._]
In this way, the fundamental “instructions” that determine the
characteristics of a cell are passed on to each new cell. Ideally, all
the trillions of cells in a particular human being have identical sets
of “instructions”.[1]
Enzymes and Genes
Each cell is a tiny chemical factory in which several thousand different
kinds of chemical changes are constantly taking place among the numerous
sorts of molecules that move about in its fluid or that are pinned to
its solid structures. These chemical changes are guided and controlled
by the existence of as many thousands of different _enzymes_ within the
cell.
Enzymes possess large molecules built up of some 20 different, but
chemically related, units called _amino acids_. A particular enzyme
molecule may contain a single amino acid of one type, five of another,
several dozen of still another and so on. All the units are strung
together in some specific pattern in one long chain, or in a small
number of closely connected chains.
Every different pattern of amino acids forms a molecule with its own set
of properties, and there are an enormous number of patterns possible. In
an enzyme molecule made up of 500 amino acids, the number of possible
patterns can be expressed by a 1 followed by 1100 zeroes (10¹¹⁰⁰).
Every cell has the capacity of choosing among this unimaginable number
of possible patterns and selecting those characteristic of itself. It
therefore ends with a complement of specific enzymes that guide its own
chemical changes and, consequently, its properties and its behavior. The
“instructions” that enable a fertilized ovum to develop in the proper
manner are essentially “instructions” for choosing a particular set of
enzyme patterns out of all those possible.
The differences in the enzyme-guided behavior of the cells making up
different species show themselves in differences in body structure. We
cannot completely follow the long and intricate chain of
cause-and-effect that leads from one set of enzymes to the long neck of
a giraffe and from another set of enzymes to the large brain of a man,
but we are sure that the chain is there. Even within a species,
different individuals will have slight distinctions among their sets of
enzymes and this accounts for the fact that no two human beings are
exactly alike (leaving identical twins out of consideration).
Public-domain text, read in full here on John Shaqi.
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