Each chromosome can be considered as being composed of small sections
called _genes_, usually pictured as being strung along the length of the
chromosome. Each gene is considered to be responsible for the formation
of a chain of amino acids in a fixed pattern. The formation is guided by
the details of the gene’s own structure (which are the “instructions”
earlier referred to). This gene structure, which can be translated into
an enzyme’s structure, is now called the _genetic code_.
[Illustration: _Stained section of one cell from salivary gland of_
Drosophila, _or fruit flies, reveals dark bands that may be genes
controlling specific traits_.]
If a particular enzyme (or group of enzymes) is, for any reason, formed
imperfectly or not at all, this may show up as some visible abnormality
of the body—an inability to see color, for instance, or the possession
of two joints in each finger rather than three. It is much easier to
observe physical differences than some delicate change in the enzyme
pattern of the cells. Genes are therefore usually referred to by the
body change they bring about, and one can, for instance, speak of a
“gene for color blindness”.
A gene may exist in two or more varieties, each producing a slightly
different enzyme, a situation that is reflected, in turn, in slight
changes in body characteristics. Thus, there are genes governing eye
color, one of which is sufficiently important to be considered a “gene
for blue eyes” and another a “gene for brown eyes”. One or the other,
but not both, will be found in a specific place on a specific
chromosome.
The two chromosomes of a particular pair govern identical sets of
characteristics. Both, for instance, will have a place for genes
governing eye color. If we consider only the most important of the
varieties involved, those on each chromosome of the pair may be
identical; both may be for blue eyes or both may be for brown eyes. In
that case, the individual is _homozygous_ for that characteristic and
may be referred to as a _homozygote_. The chromosomes of the pair may
carry different varieties: A gene for blue eyes on one chromosome and
one for brown eyes on the other. The individual is then _heterozygous_
for that characteristic and may be referred to as a _heterozygote_.
Naturally, particular individuals may be homozygous for some types of
characteristics and heterozygous for others.
When an individual is heterozygous for a particular characteristic, it
frequently happens that he shows the effect associated with only one of
the gene varieties. If he possesses both a gene for brown eyes and one
for blue eyes, his eyes are just as brown as though he had carried two
genes for brown eyes. The gene for brown eyes is _dominant_ in this case
while the gene for blue eyes is _recessive_.
Parents and Offspring
How does the fertilized ovum obtain its particular set of chromosomes in
the first place?
Public-domain text, read in full here on John Shaqi.
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