709 Tyana falls before the Mohammedans in their ravages on the Bosporus. 710 Great cruelty shown to Ravenna and the Chersonesus by the emperor. 711 Justinian overthrown by Bardanes, who becomes emperor under the name of =Philippicus=. In his reign the Mohammedans invade Spain (711) and the Bulgarians ravage Thrace (712). The Mohammedans take Antioch in Pisidia. 713 Philippicus dethroned and his eyes put out. Artemius his secretary is raised to the emperorship as =Anastasius II=. He tries honestly to bring about reforms, and sends an embassy to Damascus to arrange a peace with the Mohammedans. 715 The army determines to depose Anastasius, and chooses an obscure person, =Theodosius III=, who unwillingly assumes the purple. 716 The Mohammedans again invade Asia Minor and besiege Amorium. =Leo III the Isaurian= relieves the town, makes a truce with the besiegers, and is proclaimed emperor by the army. THE ISAURIAN DYNASTY AND SUCCEEDING KINGS (716-820 A.D.) 717 Mohammedans besiege Pergamus. They begin the siege of Constantinople, which is raised the following year. 726 The dispute over image-worship arises. Publication of the first iconoclastic decree. The great iconoclastic schism begins, immersing the empire in many calamities and revolts, leading to the final separation of the Greek and Latin churches. The Mohammedans invade Cappadocia. 727-728 Revolts in Italy and Greece. 734 Mohammedan invasion of Asia Minor. 739 Battle of Acronum. 740 =Constantine (V) Copronymus= succeeds his father. 742 Defeat of the rebel Artavasdes, who has obtained possession of Constantinople. 744-747 The Great Plague devastates the empire. 746 Mohammedan invasion of Cyprus. 750 Fall of the Omayyad dynasty. Two rival Saracen powers are formed. Ravenna taken by the Lombards. 751 Capture of Melitene and Theodosipolis by Constantine. 753 Invasion of Italy by Pepin. Council of Constantinople favours iconoclasm. 755 Invasion of Thrace by the Bulgarians. Pepin continues invasion of Italy. 757 The Bulgarians driven back to their own territory with great slaughter. 760-765 Constantine invades Bulgaria. Victory of Anchialus, 762. 766 Wreck of the Roman fleet at the mouth of the Danube. Edicts against image-worship extended and vigorously enforced. 773-774 Campaigns against the Bulgarians. Victory of Lithosoria. Peace made with the Bulgarian monarch, which Constantine breaks. 775 =Leo IV=, son of Constantine, succeeds him. He is a zealous iconoclast. He marries the empress Irene. 778 Successful campaign against the Bulgarians. 780 Capture of Semaluos by Harun-ar-Rashid. Death of Leo. =Irene= becomes regent for the ten-year-old =Constantine VI=.