Rodrigo de Valero told Egidius that the books from which he derived his knowledge were worth nothing, and that his preaching would never be admired, if he did not study the Bible. Egidius took his advice, and in time acquired a style of preaching extremely agreeable to the people, but his success raised him many enemies. The emperor gave him the Bishopric of Tortosa in 1550, which increasing the envy and hatred of his enemies, they denounced him to the Inquisition of Seville as a Lutheran heretic, for some propositions which he had advanced in his sermons, and which they separated from the other parts, to give them a different sense from what they would otherwise have had; they took advantage of the favour he showed to Rodrigo Valero in 1540 during his trial, and of some other circumstances, to injure him. Egidius was taken to the secret prisons of the holy office in 1550: he made use of this opportunity to compose his apology, which rendered the storm his enemies had raised still more violent. His simplicity had made him, in his apology, establish as certain principles, some propositions which the scholastic theologians looked upon as erroneous, and tending to heresy. The conduct and morals of Egidius were so pure, that the emperor wrote in his favour, the chapter of Seville followed his example, and (what is still more remarkable) the licentiate, Correa, Dean of the inquisitors, was touched by his innocence, and undertook to defend him against his colleague, Pedro Diaz, who bore the greatest hatred to the accused. This circumstance was particularly mortifying to Egidius, as his enemy formerly held the same opinions, and had likewise studied in the school of Rodrigo Valero. The interest which Egidius had inspired induced the inquisitors to accede to his proposal of a discussion between him and some learned theologians. Brother Garcia de Arias, of the convent of St. Isidore of Seville, was chosen; but his opinion was not deemed sufficient, and Juan Gil demanded the Dominican friar, Dominic Soto, should be summoned to the conference. This incidence retarded the trial, but Soto at last arrived at Seville. According to Gonzales de Montes, this theologian held the same opinions as Egidius; but to prevent the suspicions which might arise from this circumstance, he persuaded Egidius to draw up a sort of confession of faith. They agreed that both should write their opinions, and only communicate them to each other in public. This author states that these confessions of faith were compared, and found to accord perfectly.