Indeed already on July 23, 1484, she is lying “infirm in bed, in her room in the Women’s quarter of the Hospital, oppressed with bodily infirmity.”[13] 2. _Abnormal sensations, impressions and moods._ Her attendants are all puzzled by the multitude and intensity, the mobility and the self-contradictory character of the psycho-physical manifestations. Perhaps already before 1497 “she would press thorny rose-twigs in both her hands, and this without any pain”; and so late as about three weeks before her death “she remained paralyzed (_manca_),” and no doubt anaesthetic “in one (the right) hand and in one finger of the other hand.”--Probably again before 1497 “her body could not,” at times, “be moved from the sitting posture without the application of force.” In February or March 1510 “she could not move out of her bed”; in August, “on some occasions she could not move the lips or the tongue, or the arms or legs, unless helped to do so,--especially on the left side,--and this would, at times, last three or four hours.”--In December 1509 “she suffered from great cold,” as part of her peculiar condition; on September 4, 1510, “she suffered from great cold in the right arm.”[14] On other occasions she is, on the contrary, intensely hyper-aesthetic. Some time in February or March 1510, “for a day and a night, her flesh could not be touched, because of the great pain that such touching caused her.” At the end of August “she was so sensitive, that it was impossible to touch her very bedclothes or the bedstead, or a single hair on her head, because in such case she would cry out as though she had been grievously wounded.”--These states seem to have been usually accompanied by sensations of great heat: for on the former occasion “she seemed like a creature placed in a great flame of fire”; whilst on the latter “she had her tongue and lips so inflamed, that they seemed as though actual fire.”