As previously shown, the _liver_ is much larger, proportionately, in the carnivora; and not only is this the case, but the amount of bile secreted is far greater in the carnivora than in man. It has been found, by careful experiments upon dogs, that the quantity of bile might increase fifty per cent., and even more, under a purely meat diet; but rapidly decreased when the quantity and proportion of the meat was reduced. Thus it appears that the use of a meat diet requires a far greater degree of activity on the part of the liver than any other diet. This is amply provided for in the carnivore by the increased size and power of that organ, but in man and the frugivora such is not the case, and the result is that if meat be eaten by man, the liver is called upon to do an extra amount of work, and this may ultimately result in its premature breakdown. The _kidneys_ also are greatly affected by the diet. It is now well known that uric acid is created in large quantities by a flesh diet—the measured excretions showing that from three to ten times as much uric acid is secreted when flesh is eaten as when no meat is ingested; and when we bear in mind the exceedingly disastrous effects of uric acid upon the system, and what a powerful disease-producing agency it is, I think that we must conclude that this symptom is strongly suggestive, and strongly indicative of the fact that man cannot eat meat without running grave chances of diseasing and ruining his organism. * * * * *