"III. On the 12th of July, 1823, I saw on the sands in the bay between Saint Mary and La Goyave, at Guadaloupe, many Physalia recently cast ashore. Having a dog with me, with the assistance of my servant, I made him swallow the freshest of them, with all its filiform tentacles, pushing it down his throat, while my servant held his mouth open; five minutes after, the dog exhibited symptoms of great pain on the edges of its lips; it foamed at the mouth and rubbed it in the sand, or upon the grass, leaping about, passing its paws over its jaws, and exhibiting every symptom of excessive pain. I mounted my horse, and, in spite of its sufferings, the poor animal followed me as it was wont. After twenty minutes, when its sufferings seemed over, I had a piece of bread which I gave it, and it ate it with appetite, swallowing it without any difficulty; it only seemed to feel the pain on the edges of its mouth: it was well enough all day, and had evacuations which gave no indication that the Physalia had any influence over the digestive organs. Next day, and the day following, it was as well as usual, exhibiting no signs of inflammation either in the mouth or throat. "IV. On the 20th of the same month, I took two 'galleys' on the sea-shore and cut them in pieces; then, with a spoon, I had them forced down the throat of a puppy, which still sucked its mother; this strong dose of Physalia had no effect upon it, the tentacles having probably been surrounded by the fleshy parts of the animal in dividing it, so as not to touch the mouth: it seems probable, therefore, that the internal mucus is capable of subduing the irritation, which is so distressing when applied to membranes exposed to the external air. We swallow some things with impunity, which we could not support in the mouth if the burning substance remained there. "V. I have also procured many 'galleys' since these experiments, and having placed them in a glass tube, left them to dry and had them pulverized; twenty-five grains of this powder administered to a very young dog produced no deleterious effects. Twice this quantity administered to a young cat produced no more, nor has this surprised me; for, if the fresh animal has no poisonous properties, how can it be supposed that drying the zoophyte can have increased its poisonous properties, if it really possesses them? On the contrary, it is more reasonable to suppose that, by desiccation, the deleterious principle from any animal, whether _Physalia_ or _Holothuria_, should lose infinitely in its principle by evaporation, and other changes that heat and air produce in the process of drying. "VI. I have had a 'galley' cut into pieces, and got a fat young chicken to swallow them. It caused no inconvenience. Three hours after, I had the chicken killed and roasted; then I ate it, and made my servant eat it too. Neither of us experienced any inconvenience from it, a certain proof that it is not from eating Physalia that the fish becomes poisonous.