The pathology of influenzaWinternitz, M. C. (Milton C.)
Science
The pathology of influenza
Winternitz, M. C. (Milton C.)
Influenza
The past and family histories were unimportant. Her illness began
one week before admission with dizziness, headache, vomiting, cough,
pains in back and legs, chilly sensations, and fever. She went to
bed the day after. The acute onset became definitely worse and pains
developed in her chest. On admission she was very weak, had a
temperature of 101.4°F., a pulse of 120, and respirations of 40 per
minute. The physical examination showed a very well developed and
nourished woman who was cyanotic but not dyspnœic. The pharynx and
tonsils were definitely injected. There were signs of consolidation
at the base of the left lung. The pneumonic process gradually
increased in the left, spread to the right, and involved the greater
portion of both lungs. Otherwise the physical signs did not change
greatly during her stay of thirteen weeks in the hospital.
Thrombosis of the left femoral vein was diagnosed about two days
before her death. The temperature curve was of interest. During the
first two days in the hospital it remained at 104°F. For two weeks
it was septic in character, being 102°F. in the morning and 104°F.
in the afternoon. Then for thirty days it was practically constant
at 102°F., only to become septic again, 98.6°F. in the morning and
103.4°F. in the afternoon, and it remained so until death. The pulse
curve ran essentially parallel to the temperature curve, varying
from 100 to 140 per minute. The respirations varied between 46 and
64 per minute.
The sputum showed Type IV pneumococcus. The blood culture was
negative.
[Illustration:
FIG. XXX. AUTOPSY NO. 169 (LEFT) AND AUTOPSY NO. 97 (RIGHT). THIS
CONTRAST IN THE EXTENT OF INFLAMMATORY INVOLVEMENT BETWEEN
NEIGHBORING LOBULES IS FREQUENTLY ENCOUNTERED.
]
[Illustration:
FIG. XXXIII. GANGRENE OF THE LUNG.
]
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