The pathology of influenzaWinternitz, M. C. (Milton C.)
Science
The pathology of influenza
Winternitz, M. C. (Milton C.)
Influenza
Microscopic examination of the viscera showed acute congestion and
some degree of cloudy swelling in the liver and kidneys. The
sections of the lung through the consolidated area showed the pleura
replaced by a thick layer composed of large and small mononuclear
cells, some red blood cells, a rare polymorphonuclear cell, and
great numbers of fibroblasts and budding capillaries. Some of the
alveoli contained many red blood cells, a few polymorphonuclear and
mononuclear cells, some fibrin, and in many areas fibroblasts were
organizing this exudate (Fig. XLV). Organization was also present
around the bronchi and these contained mucus, pus, and desquamated
epithelium. Frequently strands of fibroblasts were seen sweeping
through the bronchiolar exudates, and in a few instances they had
completely filled the lumina.
II. INFLUENCE OF THE RESPIRATORY COMPLICATION OF INFLUENZA UPON
TUBERCULOSIS OF THE LUNG
Thirteen of the ninety-five cases included in this report occurred at
the United States General Hospital No. 16, one of the large tuberculosis
camps. In five instances the patients had active pulmonary tuberculosis.
The remaining eight were members of the detachment and may be added to
the eighty-two from the New Haven Hospital, making a total of ninety
cases in which there was no clinical evidence of active pulmonary
tuberculosis at the onset of the acute respiratory disease. When these
ninety cases are analyzed, it is found that only two of them show
definite activation of an old tuberculous focus (82). One has already
been referred to (Autopsy No. 209); the other, presenting a much more
acute exudative and ulcerative tuberculosis, deserves special
consideration.
_Autopsy No. 194._
A white female, aged 27 years, was admitted to the New Haven
Hospital on November 8, 1918, complaining of “cold on the chest,
fever, cough, and prostration.”
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