So far as the brute effect of the drugs is concerned, the first stage is one of physical and mental exhilaration. To this physiological fact no doubt is due the Mexican use of peyote in foot-races, in war and for allaying hunger and thirst when on fasting pilgrimages for the plant. Expression of this exhilaration by dancing is common in Mexico, and is found likewise among the Tonkawa, the Lipan and sporadically in the Plains.[32] Gross attitudinal behavior may be exhibited in extreme cases. Lumholtz[33] says of the Huichol that in a few cases a man may consume so much that he is attacked with a fit of madness, rushing backward and forward, trying to kill people, and tearing his clothes to pieces. People then seize upon him, and tie him hand and foot, leaving him thus until he regains his senses. Such occasions are thought to be due to infringements of the law of abstinence imposed upon them before and during the feast. This semi-psychotic state is no doubt as much conditioned culturally as the Malay “running amok”; in Mexico early Spanish writers repeatedly describe native visions as sometimes horribly frightening as well as sometimes laughable. Indeed, in Mexico, among the Mescalero, and the early Plains users, aggressions welling up under peyote intoxication commonly took the form of witchcraft fear and counter-witchcraft. Typically in the Plains, however, the attitude repeatedly emphasized is that of intertribal brotherhood and an individual feeling of friendliness and well-being. Nevertheless some fifty native visions collected indicate great variability in the psychic state. A Taos instance records euphoria to the point of laughter,[34] but Crashing Thunder (Winnebago)[35] experienced a state of deep depression and intense _fear_: