At about the fifth day after vaccination, and for three or four days, he is generally a little feverish; the mouth is slightly hot, and he delights to have the nipple in his mouth. He does not rest so well at night; he is rather cross and irritable; and, sometimes, has a slight bowel complaint. The arm, about the ninth or tenth day, is usually much inflamed—that is to say, it is, for an inch or two or more around the vesicles, red, hot, and swollen, and continues in this state for a day or two, at the end of which time the inflammation gradually subsides. It might be well to state that the above slight symptoms are desirable, as it proves that the vaccination has had a proper effect on his system, and that, consequently, he is more likely to be thoroughly protected from any risk of catching small-pox. 54. _Do you approve, either during or after vaccination, of giving medicine, more especially if he be a little feverish?_ No; as it would be likely to work off some of its effects, and thus would rob the cow-pox of its efficacy on the system. I do not like to interfere with vaccination _in any way whatever_ (except, at the proper time, to take a little matter from the arm), but to allow the pock to have full power upon his constitution. What do you give the medicine for? If the matter that is put into the arm be healthy, what need is there of physic? And if the matter be not of a good quality, I am quite sure that no physic will make it so! Look, therefore, at the case in whatever way you like, physic after vaccination is _not_ necessary; but, on the contrary, hurtful. If the vaccination produce a slight feverish attack it will, without the administration of a particle of medicine, subside in two or three days. 55. _Have you any directions to give respecting the arm_ AFTER _vaccination_? The only precaution necessary, is to take care that the arm be not rubbed; otherwise the vesicles may be prematurely broken, and the efficacy of the vaccination may be lessened. The sleeve, in vaccination, ought to be large and soft, and should _not_ be tied up. The tying up of a sleeve makes it hard, and is much more likely to rub the vesicles than if it were put on in the usual way. 56. _If the arm_, AFTER _vaccination, be much inflamed, what ought to be done_? Smear frequently, by means of a feather or a camel’s-hair brush, a little cream on the inflamed part. This simple remedy will afford great relief and comfort. 57. _Have the goodness to describe the proper appearance, after the falling off of the scab, of the arm?_ It might be well to remark that the scabs ought always to be allowed to fall off of themselves. They must not, on any account, be picked or meddled with. With regard to the proper appearance of the arm after the falling off of the scab, “a perfect vaccine scar should be of small size, circular, and marked with radiations and indentations.” DENTITION. 58. _At what time does dentition commence?_