CASE VI.—I adduce as an instance of another variety of dyspnœa a warehouse woman of 27, who had also lost several brothers and sisters of phthisis. Had been much depressed by nursing the last one through a long and painful illness; she came to me in June 1868, with symptoms of dyspepsia and history of attacks of urgent difficulty of breathing coming on generally at a fixed hour of 9 or 10 in the morning; occasionally after later meals; she kept constantly sighing deeply, and had various symptoms of hysterical temperament; had also cough and viscid expectoration; but a physical examination revealed nothing very definite—perhaps puerile respiration in one lung and diminished vesicular murmur in the other. She was treated for some weeks with various stomachic and tonic medicines, and went into the country for a fortnight; but the symptoms remained more or less. It was during an attack of this spasmodic or hysterical dyspnœa that I first administered oxygen to her, in proportion of 5 pints to 30 of air, and again in a double dose, only on three or four occasions. It is possible that these doses were not large enough for a fair trial; but, however, I wish to record that relief was given, but it was slight and not permanent. Eventually the patient recovered under the use of bromide of potassium and quinine. She has since married, and is well. CASE VII. _Chlorosis._—Miss P——, æt. 21, had been employed for some years with very long hours of work in a small close room; was stunted in growth, with chlorotic complexion, drowsiness, headache, palpitation, dyspnœa, and great fulness of the thyroid gland. Menstruation still occurred, though scantily, and at intervals of six to ten weeks. She came under my care in January 1868, and after regulating her hours and her food as far as possible I prescribed various preparations of iron, of magnesia, of aloes and myrrh, baths, and liniments, &c. There was a gradual improvement in her condition with occasional relapses, which obliged her to remain under treatment for many months. In October 1868 the prominent symptom was headache, violent and pulsating, and it was for this that I prescribed oxygen, after the failure of many medicines. _November 8th._—Inhaled 6 pints diluted with 30 of air; pulse 96 before commencing, had same frequency at the end; the only special symptom felt was a sense of oppression at the chest, but the headache was not so bad as usual that night.