A circular, “The Advantages of Bromidia,” makes it plain how physicians come to use a preparation like Bromidia without consideration of its potent constituent. In this circular the presence of chloral is at first frankly admitted, then it is suggested that in the combination the evil effects of chloral are completely eliminated and in the end the impression is left that Bromidia is practically innocuous. Thus at the beginning while arguing that Bromidia is better than extemporaneous preparations the chloral content is plainly acknowledged: “In the untoward effects so frequently attending the use of extemporaneously prepared mixtures of chloral and the bromides, may be found the reason for BROMIDIA’S preference when the need for a hypnotic agent arises. Were it not for the well known disadvantages of these drugs which become still more marked with their continued use, there could be no special need for such a preparation as BROMIDIA (Battle), for the therapeutic powers of chloral and the bromides are among the most positive facts in medicine.” Again: “It was to meet the growing professional demand for a combination of chloral and the bromides with their evil effects eliminated, that led to the manufacture of BROMIDIA (Battle).” Then, suggesting the indiscriminate use of Bromidia--as an entity as Dr. Wood suggests--the claim is made that: “... its constituents have been chosen with a view of enabling Bromidia to meet every requirement for an agent of its class.” “Owing to the exceptional purity of its component parts and its freedom from untoward effects when continued over long periods, this product will be found of the highest utility in epilepsy.” “... its action is that of chloral and the bromides minus their evil effects.” Finally Bromidia becomes a simple bromid preparation. Thus an advertisement reads: “Bromidia’s (Battle) Marked Sedative and Antispasmodic Qualities eminently fit it for the treatment of Maniacal Excitement, Epilepsy, Spasmodic Asthma, Convulsive Seizures of Reflex Origin, Sexual Neuroses, and other disorders attendant upon nervous irritability. “Through its exhibition, the fullest therapeutic power of the bromides may be secured with a minimum of their evil effects; a feature of the greatest service when the necessity for continued treatment becomes necessary.” In addition to the general invitation to use Bromidia in epilepsy and various nervous disorders, a circular also recommends its use in typhoid, a recommendation, which, if followed, may turn the scale in favor of a fatal result. The circular states: