Kola contains a very small percentage each of caffein and theobromin. It is impossible for the infinitesimal amounts of these alkaloids in an ordinary dose of Celerina to produce any physiologic effect. Viburnum has been called a “uterine sedative,” whatever that may be. Its only real activity is the psychic one due to its taste and odor. Celery at one time was credited with being both an antispasmodic and a nerve stimulant--a remarkable combination of opposing qualities! Scientific investigation has failed to show that celery has any physiologic or therapeutic activities. If it had the slightest medicinal value, the rational course would be to prescribe it in its fresh and natural state. The small dose contained in a teaspoonful of Celerina is inappreciable and not even equivalent to that contained in a stalk of celery. Ladyslipper, more imposing under the Latin name of “cypripedium,” is a flowering plant with a legendary reputation as an “antispasmodic and nerve stimulant.” It has been in the therapeutic scrap-heap for years. It contains a little tannic acid, gallic acid and a volatile oil. Even a tannic acid action cannot be expected from a teaspoonful of a preparation containing 20 grains of ladyslipper to the ounce. Prickly ash (xanthoxylum) has never been shown to have any activity other than that of a local irritant, especially to mucous membranes. The slight “bite” from this drug would be entirely covered up by the alcohol in Celerina. Any stimulating effect which this drug may have on the stomach is greatly inferior to that produced by a very small glass of ordinary ginger ale. In short, there is no ingredient in Celerina, except the alcohol, that has any recognizable activity; and the alcohol content is nearly as great as that of ordinary whisky. Some of the claims and recommendations for this nostrum are: “Celerina (Nerve Tonic), for Nervousness, Hysteria, Insomnia, Nervous Indigestion, Languid and Debilitated Conditions, Recovery from Alcoholic Excess.” Think of prescribing an alcoholic nostrum four times a day to promote recovery from alcoholic excess! “NEURASTHENIA: The bane of the general practitioner; the puzzle of the neurologist; the juicy fruit of the quack and faddist; the opportunity of the intelligent therapist.... For the medical treatment CELERINA is the preparation of wide utility.” The _sang froid_ with which the exploiters of this nostrum refer to other “quacks and faddists” as reaping “juicy fruit” from neurasthenics would command admiration were it not so pitiful. “Celerina has substantial endorsement in nervous disorders characterized by Aphonia (nervous).” Of course, the disappearance of nervous aphonia might follow the application of any treatment whatever, be it Eddyism, Chiropractic, Peruna or Celerina. In “CLIMACTERIC (the Menopause) flattering results have been reported from a combination of equal parts Celerina and Aletris Cordial Rio.”