The Propaganda for Reform in Proprietary Medicines, Vol. 1 of 2Council on Pharmacy and Chemistry (American Medical Association)
Science
The Propaganda for Reform in Proprietary Medicines, Vol. 1 of 2
Council on Pharmacy and Chemistry (American Medical Association)
Patent medicines
In our method of experimentation we determine the weight of the
diastase in question which will convert a given weight of starch in
uniform paste to the so-called colorless end-point in ten minutes,
that is to the point where it will no longer give any color reaction
with a standard iodin solution. The standard starch weight in 50 c.c.
always is 1 gm. or 1,000 mg. and to a series of flasks containing
this amount of starch, maintained at a constant temperature of 40 C.,
the diastase dilutions are added. These diastase dilutions are made
by dissolving small, accurately weighed amounts of the sample in
some small, constant volume of water, usually 5 or 10 c.c. and they
are then poured into the starch flasks at the right temperature, and
agitated regularly.
Tests are made by taking a few drops from each flask and mixing
with the iodin solution. The end-point is reached when a dilution
is found which, at ten minutes from the mixing time, gives no color
with the iodin reagent. The first set of tests is taken as a general
guide, and quite accurate results may be obtained in a second set of
dilutions.
We first used a sample of Taka-Diastase bought in the open market. It
was found that 140 mg. were required to convert the gram of starch as
explained. This is equivalent to a conversion of 7.14 parts of starch
by 1 part of the Taka-Diastase.
A new, and possibly fresher, sample was then obtained and the
test repeated. With this new sample it was found that 60 mg. were
necessary to convert the gram of starch to the colorless end-point
in ten minutes, from which it follows that 1 part of the ferment
will convert 16.6 parts of starch to the colorless end-point in
the same time. With a new sample of Liquid Taka-Diastase obtained
simultaneously it was found that 3.5 c.c. were necessary to convert
1 gram of starch to the colorless end-point in ten minutes. As a
fluidounce of this liquid is said to contain 20 grains of the solid
it will be seen that the results approximately agree with those of
the first sample of the solid, and that they are both very low.
Public-domain text, read in full here on John Shaqi.
Reviews
Reviews
No reviews yet
Be the first to share your thoughts on this work.
Elsewhere in the archive
Join the Discussion
Join the discussion
Sign in to leave a comment or review.
Sign InorCreate an account