The Propaganda for Reform in Proprietary Medicines, Vol. 2 of 2Council on Pharmacy and Chemistry (American Medical Association)
Science
The Propaganda for Reform in Proprietary Medicines, Vol. 2 of 2
Council on Pharmacy and Chemistry (American Medical Association)
Patent medicines
Kochs concluded from his analysis that Ophthalmol had the properties
of rancid olive oil containing about 6 to 7 per cent. mineral oil. The
oil contained no nitrogen, left no ash on ignition and though traces of
iodin were claimed to be present, no iodin could be found.
It is recommended that Ophthalmol be rejected first, because the use
in the eye of an irritant of secret composition and uncertain activity
is unscientific and against the interest of public health; second,
because Ophthalmol is of secret composition (the composition claimed
being practically meaningless), and, third, because no evidence has
been submitted to substantiate its claimed superiority over established
methods of treatment. The Council declared Ophthalmol inadmissible to
New and Nonofficial Remedies.--(_From The Journal A. M. A., July 6,
1918._)
SILVOL INELIGIBLE FOR N. N. R.
Report of the Council on Pharmacy and Chemistry
The following report on Silvol (Parke, Davis & Company) was adopted by
the Council and its publication authorized.
W. A. Puckner, Secretary.
The Council took up the consideration of Silvol (Parke, Davis &
Company) because of inquiries received. The following report was
submitted by the referee in charge of silver preparations:
Silvol (Parke, Davis & Company) is a silver-protein preparation of the
Argyrol type. Like Argyrol, it is said to contain about 20 per cent.
of silver. The referee finds that, like Argyrol, it is nonirritant to
the nasal mucosa in a 10 per cent. solution; does not precipitate with
chlorid; dissolves in water readily; a 25 per cent. solution has a high
specific gravity (Silvol, 1.137 at 20 C.; Argyrol, 1.147 at 20 C.), and
is not very viscid (viscosity, 1.25). A 1:1,000 solution of Silvol is
clear and about 50 per cent. deeper in color than a solution of Argyrol
of the same strength.
Silvol differs from Argyrol mainly in that its solutions yield a fine
precipitate with egg albumin (under suitable conditions), while Argyrol
is nonprecipitant; and in that Silvol solutions are not so effectively
decolorized by Lloyd’s reagent.
The manufacturers did not reply to an inquiry with regard to the
basis for the claims made for Silvol (see Appendix). The referee was
therefore obliged to deduce these claims from the firm’s advertising
matter. About the same claims are made for the local use of Silvol as
are generally made for Argyrol. These may be accepted without detailed
evidence in view of the similarity of the two preparations.
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