It has already been remarked, that a certain elevation of temperature was necessary to the production of this poison, though what the precise degree is, has not been ascertained; and as this is, chiefly, what distinguishes the regions or periods of the year which generate malaria, I need not make two divisions of season and climate. If, however, this temperature is not fixed, it will perhaps suffice for our present purposes to say that the greater part of Scotland, whether as to climate or season, seems incapable of generating the disease from this cause; though there are exceptions of a permanent nature, or exceptions of climate, as was perennially true of the Carse of Gowrie before its drainage; while there are others which happen when, as in the last year, there has been a peculiarly hot summer, and which are exceptions of season. And thus it is as to more northern regions; where a hot summer becomes more than an equivalent for an average low temperature; as an example of which, there is no place where intermittents are more severe and abundant than at Stockholm. But the extreme of evil from this cause occurs, as is well known, in the tropical climates; appearing almost proportioned to the heat of the climate, and what is important to observe to the moisture also. The destructive effects of certain parts of Africa, India, America, and so forth, are familiarly known; and [p040] it is in these countries especially, that the diseases from this source constitute nearly the entire mortality of the human race. And thus, for Europe, it is in Spain, Italy, and Greece, and chiefly on their Mediterranean shores, that the activity of malaria scarcely yields to that of the intertropical climates; while in France, Holland, Germany, Hungary, and with us, in a far less degree, the production will be found regulated by the heat of the summers, all other circumstances being the same. And if we thus account for the variations in the quantity and virulence of diseases in any given country, for noted seasons of epidemic in the countries which I have just named, and for the great prevalence of fevers among ourselves during the last few years, and particularly in the last summer, there is another point of scarcely inferior importance to be taken into the consideration, independently of that which relates to peculiar winds as connected with the propagation of this poison;—and this is, moisture.