Whether the changes as to temperature and moisture which occur within the space of twenty-four hours, affect the production or propagation of malaria, I will not here inquire minutely, from the fear of prolonging this very limited paper; but the general facts, as to its effects, are these: If we commence with the sun on the meridian, there appears, even in the worst climates, very little hazard of fever; while in Italy, it is believed that there is, generally, little or no hazard, except in some peculiarly pestilential places, and under particular kinds of inattention or neglect. Either the malaria is decomposed or destroyed by the heat, or else the air from its dryness ceases to be a conductor; but as evening approaches, its influence becomes powerful and dangerous, being supposed most generally to extend all through the night; while in some parts of that country it is a popular belief that it terminates before midnight, or with the precipitation of the atmospheric moisture. Whether this last opinion is true or not, the general fact explains the popular [p043] belief, and truth, respecting the poisonous effects of dew in the hot climates; the supposed pernicious quality of this depending evidently on the malaria by which its formation is accompanied. And in this case it is probable that the evil arises, not from a fresh or peculiar generation of malaria, but from the mere fact that the moist atmosphere is a better conductor than a dry one. Not to be unnecessarily minute, we thus also explain the danger of exposure to the morning air in similar situations; the facts, as they relate to the conducting of malaria, being the same, though the meteorological circumstances are somewhat different. Hence, also, we see why the grey mists which hang over wet grounds in the evening in our own climate, are esteemed pernicious; the truth, however, being, that they are perfectly innocent at certain seasons and in certain places—as in the greater part of Scotland, for example, or in those places and at those periods where malaria is not produced. The distinction is valuable, because of the inconvenience of restrictions on this subject, and because to know where the hazard really lies is to reduce those, and also to prevent the infraction of rules by not extending them beyond what is necessary; and thus also by seeing what are the real dangers of what is called night air, we more easily avoid them. Night air is avoided now, under a false philosophy, because it is cold or damp, or for some other vague reason; while the dangers from mere dampness or cold are as nothing compared to those here pointed out; which also occur precisely where they are least feared, namely, in warm summer evenings, after refreshing showers, and so forth. Hence it is that fevers are produced in summer, in rural situations, and especially perhaps amid the most engaging scenery, by evening walks and exposure to what is naturally