And if I cannot detail all the various modes in which these circumstances may be modified, and how their effects may vary, it will be useful to make one remark on an error as relating to it which is universal among us, and into which even Lind has fallen. The error is, to think that the rain, the moisture, or the cold is itself the cause of the diseases which follow this state of things; while it is obviously a case analogous to that of Africa, if less severe, and the malaria is produced by these circumstances on soils which I formerly pointed out, and which Lind, like every one else, had neglected. But if I must pass over many interesting and useful conclusions to be drawn from these general principles, there is one fact which I must notice, and it is this:— In spring, the combination of heat and moisture, easily explained, generates, most commonly, intermittents; or the effect of the malaria at this season differs from what it does in autumn: while as the heat advances and the ground dries, this kind of fever ceases to be produced, a new species, or the summer remittent, taking its place when the heat and the moisture of autumn begin to act. But under peculiar seasons of heat and moisture with us, it sometimes occurs, as it has done [p042] within the last years, that the intermittent season runs into the remittent one, or there is no midsummer interval of freedom from disease; while it has also happened, and in some parts of England in this last year, that what would have been intermittent fever in other years has been remittent; or the common fever has occupied the whole summer, continuously, even from March to November, as is the case in the worst regions of southern Europe. Now, under these exceptions, which I was bound to explain, the commencement of intermittent, or of vernal ague, may be fixed about the middle or end of March, and its termination similarly in May; while that of remittent may be placed in the beginning of August, and its termination with the middle or end of October. How these periods may otherwise be affected by the more or less insalubrious nature of the district or place, will easily be judged of by those who will reflect for themselves on what I dare not explain, lest I should infringe too far on my limits. All else that I can venture on, as to this part of the question in hand, relates to the effects of the different times of the day on the production, propagation, or influence of malaria, and it is one which is of no small importance in a practical view.