_Couns. for the Prisoner._ Mr. President, and gentlemen of the jury, the Prisoner at the bar stands indicted for preserving the lives of his Majesty’s liege subjects, by secret medicines and modes of practice, and by inoculating, or causing to be inoculated, divers persons, &c. With regard to his preserving the lives of the King’s subjects, it has been so insufficiently proved, that we shall not take up your time in disproving it; but as to his secret medicines, we shall shew you that the ingredients of which they are made are certainly known, and consequently that they are not secret medicines. We shall prove to you, by undeniable evidence, that the same medicines have been long recommended and administered for the same purposes, and with equal success. And we shall, last of all, produce a witness of unquestionable authority, who will convince you that the successful practice of inoculation does not depend on any peculiar medicine whatsoever, and consequently that the Prisoner is perfectly guiltless of the crimes of which he stands accused. Call Dr. Thomas Ruston. Dr. THOMAS RUSTON sworn. Pray, Dr. Ruston, have you any knowledge of the composition of certain medicines used by the Prisoner at the bar, in his practice of inoculation? _Dr. Ruston._ I believe I have. _Couns. for the Pris._ What is the form of these medicines? _Dr. Ruston._ Powders, pills, and drops. _Couns. for the Prisoner._ What are the ingredients which compose the powder? _Dr. Ruston._ I verily believe the powder to consist entirely of calomel and æthiops mineral. _Couns. for the Pris._ What are your reasons for thinking so? _Dr. Ruston._ My reasons are founded on chemical experiment and analogy. _Couns. for the Prisoner._ What experiment and what analogy? _Dr. Ruston._ 1st. To a small quantity of Mr. Sutton’s powder, which was of a greyish colour, I added a few drops of volatile alkali, which immediately changed it to a deep black. 2dly. To a small quantity of the same, a few drops of a solution of salt of tartar were added, which produced the same colour. 3dly. A few drops of lime-water were added, which also changed the powder black, but not quite so black as in experiment 1 and 2. The colour and weight of Mr. Sutton’s powder were exactly imitated by the addition of six grains of æthiops to ten grains of calomel, and by repeating the above experiments with this composition, it was found to exhibit exactly the same phenomena. _Couns. for the Prisoner._ Now, Sir, as to the pills? _Dr. Ruston._ The pills, from their smell, taste, colour, and effects, are evidently no other than the well-known _pilulæ cochiæ_, with a small addition of calomel. _Couns. for the Prisoner._ Did you make no experiment with the pills?