“Exper. No. 121, was made on a dog of about 14 kgr. weight, very thin, whose blood was particularly poor. Blood was drawn from the carotid artery, the jugular vein, and the vena cava superior at the same time, the last drops of which already thickened in the glass cannula. Respiration had ceased. Only once after a long rest, did the dog draw a deep breath with open mouth as usually happens immediately before death. The pulsations of the heart were scarcely perceptible. I then tried electric stimulation of the nervus vagus, after dissecting it out, but without causing any pulsation of the heart or breathing, either during the stimulation or when it ceased. Death was undoubtedly near. I then injected into the jugular vein a solution of common salt. Tetanus followed each injection--immediately afterwards the heart began to beat again and the blood streamed out of the arteries. When the bleeding ceased, I again injected the solution rather weaker than at first. No cramps followed but the flow of blood continued. The third injection produced the same result, but death followed soon after. The whole experiment had lasted an hour and a-half.”--“_Ueber die Ausflussgeschwindigkeit d. Blutes_,” _etc._, Pflüger’s _Archiv._, Vol. XXII., pp. 547-8. =Naunyn, Bernhardt.= B. in Berlin, 1839. Studied at Bonn and Berlin. Asst. Med. Clin., Berlin, under Prof. Frerichs, 1863; Prof. Med. Clinic. Dorpat, 1869; Prof. Berne, 1871; Prof. Med. Fac. Univ., Königsberg, 1872. Co-editor with Klebs and Schmiedeberg of “Archiv für experimentelle Pathologie.” Author of “Handbuch der Intoxicationen” and “Handbuch der speciellen Pathologie,” jointly with R. Boehm, 1874; jointly (with Schreiber) of “Experiments on compression of the brain,” Arch. f. exper. Pathol. u. Pharmak., Vol. XIV., No. 2, p. 1. Contrib. various articles to “Du Bois Reymond’s Archiv.”; also to Ziemssen’s “Cyclopædia of Medicine.” “The authors [B. Naunyn and Schreiber] have experimented upon dogs. A trephine is applied to the parietal bone. A tube is inserted into the opening thus made. Besides this another tube is brought into communication with the cerebro-spinal cavity on a level with the swelling formed by the meninges round the cauda equina. For this purpose it is sufficient to take out a few of the spinal apophyses of the corresponding vertebræ. One obtains thus, as it were, two receptacles communicating by the intermediary of the cephalo-spinal liquid, and it becomes easy to augment the pressure of this liquid.… Pain is one of the very first results produced, and it is the more intense, if the pressure be immediately brought to its greatest height. Soon, convulsions follow. These seldom are epileptiform.… Breathing becomes slower, then irregular, then disappears.”--_Archives Générales de Médecine_, VIIᵉᵐ. Série, Vol. I., 1882, p. 743. =Nepveu, G.= Surgeon, Paris; form. Res. Hosp. Sur., La Pitié Mem. Chir. Soc. Paris.