It may be said here incidentally that leaves of the very best tobaccos which are defective merely in size, or color, etc., are put through exactly the same processes as the choicer quality leaves, and are used in the manufacture of the popular priced machine-made "little cigars" and "cheroots." It will be necessary now to digress for a short time and consider what happens during the process of fermentation. FERMENTATION OF TOBACCO The fermenting of tobacco leaf has for its principal objects, (1) the removal of acrid matters, (2) the fixing of the color, and (3) the production of flavor. Fermentation can only take place under suitable conditions of heat and moisture, and is essentially a chemical process during which certain organic compounds stored in the plant are split up and others formed. A certain amount of fermentation takes place in the curing houses during the "yellowing" of the leaf after it has been harvested, but as we have seen the main process of fermentation does not occur until it is "rehandled" by the manufacturers. The general opinion held at present as the result of investigation is that the transformations which are effected in the leaf are purely the result of chemical processes. As the plant slowly dies and decomposes special ferments are produced. These ferments set up an oxidization process which splits up the complex organic compounds which still exist in the leaf cells. The starch in the plant is changed into sugar which is slowly consumed. There is a decrease in the fats and gummy substances, also in nicotine and nitrogenous compounds, and there is a formation of certain organic acids such as malic, citric and oxalic which are essential in the production of flavor. Briefly it may be said that the process is an attempt by the plant to prolong its existence by feeding on its own substance, by drawing on its own reserves and on its own structure for the food which its cells no longer receive through the natural growing process. When the struggle is over the "fermentation" is complete. The necessity for maturing tobacco has long been known but the exact nature of the changes that take place during the process were not understood. Since the discoveries of Louis Pasteur regarding the part played by bacteria in general fermentative processes it has been generally claimed by bacteriologists that the changes wrought in the leaf and the production of flavor are solely the work of bacteria. Although this view has not been proved it has never been fully disproved, and there appears to be no doubt that the microbes known to exist in the leaf during the fermentation process play an important part in the process. Fermentation can only take place as stated under suitable conditions of heat and moisture and these are the conditions which favor the development of microbes and enable them to work. The results obtained are probably partially due to chemical action and partly to bacterial action, the two being complementary to each