Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physicChristison, Robert, Sir
Science
Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physic
Christison, Robert, Sir
Medical jurisprudence; Toxicology
I am far from desiring to encourage rashness of decision, or to revive
the loose criterions of poisoning relied on in former times. But there
cannot, in my opinion, be a rational doubt that in the instance of
sulphuric acid there may often be distinct exceptions to the general law
regarding the feebleness of the evidence from morbid appearances; and
that a witness would certainly be guilty of thwarting the administration
of justice, if, relying on general rules, he refused to admit such
exceptions. What natural disease could produce appearances like those
described above? Assuredly no form of spontaneous perforation bears any
resemblance to that caused in most cases of death from sulphuric acid;
nor is it easy to mention any combination of natural diseases which
could produce the peculiar conjunction of appearances remarked in the
case of the man Humphrey.
SECTION IV.—_Of the Treatment of Poisoning with Sulphuric Acid._
Since this acid and the other mineral acids act entirely as local
irritants, it may be inferred that their poisonous action will be
prevented by neutralizing them. But in applying that principle to the
treatment it is necessary to bear in mind their extremely rapid
operation; for if much time is lost in seeking for an antidote,
irreparable mischief may be caused before the remedy is taken. Should it
be possible then to administer chalk or magnesia without delay, these
are the antidotes which ought to be preferred; but it may be well for
the physician to remember, that in the absence of both he may at once
procure a substitute in the plaster of the apartment beat down and made
into thin paste with water. M. Chevallier, in a paper on the antidotes
for the mineral acids, quotes five cases of poisoning with sulphuric
acid and two with nitric acid, where life seems to have been saved by
the speedy and free administration of magnesia, although in some cases
so large a quantity as two ounces of the poison had been
swallowed.[299]—A solution of soap is another antidote of no small
value. While the antidote is in preparation, the acid should be diluted
by the free use of any mild fluid, such as milk or oleaginous
matters.—The alkaline bicarbonates are also excellent antidotes; but
their carbonates are ineligible, being themselves possessed of corrosive
properties. In a paper on poisoning with the mineral acids by Dr.
Lunding of Copenhagen, the author is disposed to ascribe the large
proportion of deaths in his practice to the system pursued in the
Copenhagen hospital of administering carbonate of potass as an antidote
daily for weeks together.[300] On the other hand however it may be
mentioned, that in a late memoir, on this description of poisoning Dr.
Ebers of Breslau endeavours to show, that there is no reason to dread
the administration of the alkaline carbonates, even the carbonate of
potash, provided they be given with mucilaginous fluids and syrup in a
rather concentrated form; and he gives three cases illustrative of the
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