Then followed a long period of uneventful routine service in garrisons at Detroit and at Sackett's Harbor, until in the summer of 1852 his regiment was sent to the Pacific coast via the Panama route. The crossing of the isthmus was a terrible experience, owing to the lack of proper provision for it and to an epidemic of cholera. The delay was of seven weeks' duration, and about one seventh of all who sailed on the steamer from New York died on the isthmus of disease or of hardships. Lieutenant Grant, however, had no illness, and exhibited a humane devotion to the necessities of the unfortunate, civilians as well as soldiers. His company was destined to Fort Vancouver, in Oregon Territory, where he remained nearly a year, until, in order, he received promotion to a captaincy in a company stationed at Humboldt Bay in California. Here he remained until 1854, when he resigned from the army, because, as he says, he saw no prospect of being able to support his family on his pay, if he brought them--there were then two children--from St. Louis, where Mrs. Grant had remained with her family since he left New York. His resignation took effect, following a leave of absence, July 31, 1854. There was another cause, as told in army circles, for his resignation. He had become so addicted to drink that his resignation was required by his commanders, who held it for a time to afford him an opportunity to retrieve his good fame if he would; but he was unable. Through what temptation he fell into such disgrace is not clearly known. But garrison posts are given to indulgences which have proved too much for many an officer, no worse than his fellows, but constitutionally unable to keep pace with men of different temperament. It might be thought that Grant was one unlikely to be easily affected; but the testimony of his associates is that he was always a poor drinker, a small quantity of liquor overcoming him. He was now thirty-two years old, a husband and father, discharged from the service for which he had been educated, and without means of livelihood. His wife fortunately owned a small farm near St. Louis, but it was without a dwelling house. He had no means to stock it. He built a humble house there by his own hard labor. He cut wood and drew it to St. Louis for a market. In this way he lived for four years, when he was incapacitated for such work by an attack of fever and ague lasting nearly a year. There is no doubt that the veteran and his family experienced the rigors of want in these years; no question that neither his necessities nor his duties saved him from being sometimes overcome by his baneful habit.