"I think that, with regard to an experimenter--a man who conducts special research and performs an experiment--he has _no time, so to speak, for thinking what the animal will feel or suffer_!" Of Magendie's cruel disposition there seems only too abundant evidence. Says Doctor Elliotson: "Dr. Magendie, in one of his barbarous experiments, which I am ashamed to say I witnessed, began by coolly cutting out a large round piece from the back of a beautiful little puppy, as he would from an apple dumpling!" "It is not to be doubted that inhumanity may be found in persons of very high position as physiologists. _We have seen that it was so in Magendie._" This is the language of the report on vivisection, to which is attached the name of Professor Huxley. But the fact which, in my own mind, constitutes by far the strongest objection to unrestrained experiments in pain, is their questionable utility as regards therapeutics. Probably most readers are aware that physiology is that science which treats of the various functions of life, such as digestion, respiration and the circulation of the blood, while therapeutics is that department of medicine which relates to the discovery and application of remedies for disease. Now I venture to assert that, during the last quarter of a century, infliction of intense torture upon unknown myriads of sentient, living creatures, _has not resulted in the discovery of a single remedy of acknowledged and generally accepted value in the cure of disease_. This is not known to the general public, but it is a fact essential to any just decision regarding the expediency of unrestrained liberty of vivisection. It is by no means intended to deny the value to therapeutics of well-known physiological facts acquired thus in the past--such, for instance, as the more complete knowledge we possess regarding the circulation of the blood, or the distinction between motor and sensory nerves, nor can original investigation be pronounced absolutely valueless as respects remote possibility of future gain. What the public has a right to ask of those who would indefinitely prolong these experiments without State supervision or control is, "What good have your painful experiments accomplished during the past thirty years--not in ascertaining facts in physiology or causes of rare or incurable complaints, but in the discovery of improved methods for ameliorating human suffering, and for the cure of disease?" If pain could be estimated in money, no corporation ever existed which would be satisfied with such waste of capital in experiments so futile; no mining company would permit a quarter-century of "prospecting" in such barren regions. The usual answer to this inquiry is to bring forward facts in physiology thus acquired in the past, in place of facts in therapeutics. Thus, in a recent article on Magendie to which reference has been made, we are furnished with a long list of such additions to our knowledge. It may