For the cure of corpulency, diminution of food of a nutritious nature has been generally recommended; added to this, little sleep and much exercise are advised. Acids to reduce fatness are frequently administered, but have done considerable mischief. Amongst other wonderful accounts of their efficacy in such cases, it is related of a Spanish general who was of an enormous size, that he drank vinegar until his bulk was so reduced that he could fold his skin round his body. For a similar purpose soap has been frequently recommended, particularly by Dr. Flemyng. He began this experiment with one of his patients who weighed twenty stone and eleven pounds (jockey weight): in July 1754, he took every night a quarter of an ounce of common Castile soap. In August 1756 his bulk was reduced two stone, and in 1760 he was brought down to a proper condition. Darwin is of opinion that salt and salted meat are still more efficacious than soap. All these experiments, however, are in general not only useless but pernicious, and frequently prove fatal. Mr. Wadd, from whose curious work on corpulence much is extracted in this article, properly observes that, "certain and permanent relief is only to be sought in rigid abstemiousness, and a strict and constant attention to diet and exercise." Dr. Cheyne, who weighed thirty-two stone, reduced himself one-third, and enjoyed good health till the age of seventy-two. Numerous instances of the kind are mentioned, where journals of gradual reduction were kept: the following is an abstract of one of them, in the case of a person who, on the 17th June 1820, weighed twenty-three stone two pounds:-- June 17 23 stone 2 pounds. July 27 21 " 10 " September 10 20 " 7 " October 10 19 " 3 " November 10 18 " 11 " December 10 18 " 4 " December 25 18 " 1 " In another case, attended by Dr. Gregory of Edinburgh, the patient weighed twenty-three stone, and by a regular system of diet was brought down to fifteen stone. In this instance brown bread, with a certain quantity of bran in it, was employed; and it is well known that the alimentary secretions are materially altered by the quality of bread. The article of drink also requires much attention. Corpulent persons generally indulge to excess, and in this case, every endeavour to reduce them will be vain. We frequently see our jockeys reducing themselves to the extent of a stone and a half in the week. A lower scale of diet is by no means as injurious as it is generally supposed; the English prisoners made by Tippoo Saib, though kept upon a scanty pittance of bread and water, found themselves in better health than before, and some of them were cured during their captivity of liver complaints of long and severe duration. One of the most corpulent persons known was Mr. Lambert, of Leicestershire, who weighed fifty-two stone eleven pounds (14 lbs. to the stone).