The injurious effects of taking cold or chilling the body or any part of it, have been the subject of special inquiry in Germany. The mucous membrane and the skin seem the most sensitive to sudden changes from a warm to a colder atmosphere, but observations have already proven that besides the usual catarrhal inflammations, there are other inflammatory conditions that are developed. The kidneys, lungs, and liver have been found to be the seat of inflammations in a series of experiments that were made with rabbits that were removed from a warm to a much colder apartment, and from this may be inferred that these conditions originate similarly in the human subject. The logical conclusions of these researches have been, that the chilled or cooled blood becomes chemically altered and acts as a direct irritant in the small capillary vessels, and by that means all the phenomena of inflammation of the tissues are excited, and these of course develop wherever the cold may strike or locate. When we speak of a slight or a bad cold, we cannot form the least idea of the remote effects that the cold may bring about. It may lay the foundation of a nephritis or Bright’s disease of the kidneys, or some other lesion, and that it often gives rise to vaginal and uterine catarrh is as certain as that it gives rise to nasal catarrh or a cold in the head. An aptitude to take cold grows with each repetition of the attack and the prolonged duration of the acute catarrhal symptoms. And for that reason persons grow into the habit of taking cold upon the slightest exposure or change of temperature. At this stage of catarrh there is an abnormal sensitiveness of the mucous membrane and skin, in which the slightest draught of air or even passing from one room to another occasions an attack of sneezing or a chill and other symptoms that will indispose the patient for several days. The great majority of individuals have a natural predisposition to certain diseases. In anatomy the body has been divided into systems. A system is an assemblage of organs composed of the same tissues and intended for similar functions, as the circulatory system, the nervous system, the muscular system, the cutaneous system, etc.; these systems are all liable to particular diseases. In one person the mucous membrane of the respiratory system is the most sensitive part of the body, while in another, and especially in women, it is the mucous membrane of the genito-urinary system. In other words, one person will take a cold and it will settle in the head or on the bronchial tubes, while another from the same exposure will get a catarrhal inflammation of the bladder or womb; this is only explained on the theory of natural predispositions, and, perhaps, hereditary taints.