But so far is this heinous charge of committing _murder_ to discredit the powder from being supported by any shadow of proof, that physicians, on the contrary, have been complaisant to excess, or culpably indolent, in suffering the many _misrepresentations_ concerning this medicine to pass uncensured and unexposed; and those who, from the most laudable principles, have refused to adopt it, are wanting to themselves, to their profession, and to the public, in neglecting to explain the honourable principles on which they have acted; while others from different motives, _which they can best justify to themselves_, have acquired fame and fortune by a _studied_ compliance with the popular prejudices in favour of this fashionable remedy. In the course of more than twenty years practice, though I have never prescribed this medicine, yet, I have not, after fairly declaring my opinion, opposed its being given, when desired by the sick or their relations; and as the cure, where I have been concerned, has been wholly committed to it, without the addition of any medicine, or even regimen, excepting what is prescribed in the printed directions, or what the Inventor himself has ordered, some fair opportunities have occurred of observing its effects, to which, and to every other information that could be obtained, with a mind open to conviction, I have carefully attended. But in this, as in all our former researches, the evidence has been unfavourable to the fame of the powder. In some instances it has occasioned fainting, convulsions, and other violent symptoms, which terrified those who gave it. In all which I have seen, it has proved unsuccessful, though, in some cases the cure has afterwards been accomplished by safer methods; and in those where it was too late to use other remedies, the sick have died, although it was probable they might have recovered by a different management, which has succeeded in similar instances, but from an abused and misplaced confidence, has too often been set aside to make way for this favourite medicine. An argument still remains in favour of the powder drawn from the credit due to its Inventor. If that is impeached by what has already been advanced, it is only by the force of the evidence, since all personal application has been avoided. But as the reputation of the medicine is chiefly supported by an implicit confidence in the Inventor, it is necessary, however unpleasing, that this should also be considered.