[39] The word reguline signifies royal, and has been applied by chymists to the harder or more fixed parts of minerals or metals. Hoffman uses reguline and arsenical indifferently when applied to antimony; and Carthusier asserts that the intimate union of the reguline part with the arsenical principle of antimony, is the cause of its being caustic, drastic, emetic, and virulent. La parte reguline est etroitement unie au principe arsenical, qu’elle est par elle-meme caustique drastique, emetique, et virulente. Matiere Medicalle, tom. ii. sect. xv. chap. v. De l’antimoine crud. A Paris, 1765. [40] Observationes Physico-Chymicæ, p. 251 & 252. [41] Newman, p. 146. [42] Opuscula Chymico-Physico-Medica, p. 434-441. [43] In a treatise on the medical virtues of poisons, published in 1702. [44] In an inaugural speech printed in 1700. This and the last quoted author I have not seen. [45] Observations, on fevers, p. 42, and 204, published at Hanover in 1745. [46] Cours de Chemie, p. 374. [47] This matter is explained in a letter from Doctor De Haen, of Vienna, to a physician in England. I have, _says this celebrated physician_, made many experiments with hemlock, in consequence of an order from high authority: the result was, that not one of one hundred and twenty patients was cured or relieved by it; many grew worse, and seven unhappy women, with cancers in their breasts, perished in my hands, some of whom might have been saved by the knife. How did I intreat those to whom it belonged to use more precaution, or at least to suspend publishing in praise of poisons, till repeated trials had been made by several hands, lest the public faith should be abused, and the author rendered ridiculous in the face of the universe. But my remonstrances were fruitless, and, to my great concern, my best friend abruptly fell out with me, and I have incurred the disgrace of the best of sovereigns. Since I have spoke my sentiments freely, I am looked upon as the chief of heretics, as an enemy of the public and of the author’s reputation; and for this reason I have been unhappily disgraced, and defamatory libels, of the most virulent kind, have been printed against me. I expect yet more terrible storms; however, I adore that Providence which directs all for his glory and my good, from whom I should deserve a disgrace infinitely more fearful than that which I now suffer, if for the sake of transitory glory, perishable treasures, or tranquillity of life, that may be taken from me in this world, I _should become a confederate with those who have thus infamously abused the publick confidence, to the disgrace of physick_. See Medical Museum, vol. III. London, 1764. [48] Cronstedt, Hoffman, Stahl, &c. &c. [49] See Hoffman’s Physico-Chymical Observations. Of the wonderful, virulent and medical powers of antimony, and by what means the one may easily be changed into the other.