Now it often happened that, after a father and mother had taken the utmost care of the education of their children, they were frustrated of all their hopes in an instant. The small-pox getting into the family, one daughter died of it, another lost an eye, a third had a great nose at her recovery, and the unhappy parents were completely ruined. Even, frequently, when the small-pox became epidemical, trade was suspended for several years, which thinned very considerably the seraglios of Persia and Turkey. A trading nation is always watchful over its own interests, and grasps at every discovery that may be of advantage to its commerce. The Circassians observed that scarce one person in a thousand was ever attacked by a small-pox of a violent kind. That some, indeed, had this distemper very favourably three or four times, but never twice so as to prove fatal; in a word, that no one ever had it in a violent degree twice in his life. They observed farther, that when the small-pox is of the milder sort, and the pustules have only a tender, delicate skin to break through, they never leave the least scar in the face. From these natural observations they concluded, that in case an infant of six months or a year old should have a milder sort of small-pox, he would not die of it, would not be marked, nor be ever afflicted with it again. In order, therefore, to preserve the life and beauty of their children, the only thing remaining was to give them the small-pox in their infant years. This they did by inoculating in the body of a child a pustule taken from the most regular and at the same time the most favourable sort of small-pox that could be procured. The experiment could not possibly fail. The Turks, who are people of good sense, soon adopted this custom, insomuch that at this time there is not a bassa in Constantinople but communicates the small-pox to his children of both sexes immediately upon their being weaned.