An Essay on the Effects of Opium. Considered as a PoisonAwsiter, John
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An Essay on the Effects of Opium. Considered as a Poison
Awsiter, John
Opium -- Toxicology
The Use of Acid in this Case was, in a manner, forbid me, from the
natural Tendency of the Humours in young Children to such Ferments; I
therefore avoided it, till obliged by the Violence of the Effects
(acting after _Harris de Morbis acutis Infantum_, p. 102. _Quod ad
convulsiones spectat, ab Acrimonia Materiæ Morbificæ propaginem Nervosam
Extimulante ut plurimum pendentes, Testacea nostra, et maxime, si
Castoreum iis adjiciatur, &c._
As my Patient had the nocent Dose given her at Night, the Effect was not
perceived until the next Morning, when they found her, with her Eyes
closed, and insensible to the taking of Aliment and Drinks, in
consequence of which, I was called to her, and ordered as follows:
Take of Castor Water, one Ounce and a half; Crabs Claws and Cordial
Confection, each one Scruple; Syrup of Saffron, two Drachms; Tincture of
Castor, twenty Drops; mix them, and give a large Spoonful often.
A Blister was applied to the Back, notwithstanding which, the
Convulsions encreased, with short Intervals of a total Relaxation, to
which Infants are very liable in most Illnesses, owing to the natural
Moisture of their Bodies; I then gave the following:
Take of simple Pennyroyal Water, two Drachms; the Cordial Confection,
half a Scruple; Powder of _Russia_ Castor, three Grains; strong Cinnamon
Water and distilled Vinegar, each half a Drachm; mix them for a Draught,
to be given as soon as possible.
Soon after taking this Medicine, my little Patient recovered from her
Convulsions, opened her Eyes, and cried.
I then gave her a Powder of Rhubarb and Jalap corrected, which, in the
Course of the Day, produced several Stools, that smelt inexpressibly
strong; the Fits left the Child that Evening, and, in a few Days, she
was entirely recovered.
It is necessary to observe, that I continued her Testacea Powders for
several Days, to correct any Disposition there might be to Acid Ferments
in the first Passages, after their being so injured by the Power of the
Sleeping Medicine.
It is also remarkable, that, in this Case, the Effect of the Poison upon
the Child was not so sudden or violent, as on an Adult; for, I observed,
the Power of it was encreased the ensuing Day; whereas a grown Person,
if he escapes the extream Action of the Opiate for the first twelve
Hours (which was about the Interval of Rest, from the Time of her taking
it, until I saw her) his Symptoms afterwards grow mild, and he, in a
Manner, out of Danger. I presume that this After-operation of the Opium
on the Child, might be occasioned by a great quantity of Phlegm, that
had invested, at that Time, the Coats of the Stomach. The Phlegm raised
by young Children, is commonly deglutiated, and thereby might defend her
Stomach from the Violence of the Poison, until such Time as a Portion of
that Phlegm had passed into the Intestines, and thence had given the
Opiate Room to penetrate and cummunicate its full Power to the Body.
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