These calculations agree pretty nearly with estimates published in the year 1820, by Sir Gilbert Blane, founded on similar documents. His calculations extend to the parishes not included within the bills of mortality, and he comes to the following conclusion on the subject:—“It appears, therefore, that even under the very imperfect practice of Vaccination, which has taken place in the metropolis, 23,134 lives have been saved in the last fifteen years, according to the best computation that the data afford”—(Sir G. Blane on Vaccination, p. 7). But however remarkable and satisfactory this immense saving of human life, in the country where Vaccination originated, may appear, as an unanswerable evidence of its efficacy, the result has been still more decisive in many foreign countries, where it has been much more generally employed. In proof of this, I shall again quote the very valuable little work of Sir Gilbert Blane, (which, by the way, I should strongly recommend to the attention of the public, as containing much valuable matter and sound argument within a very small compass). He states, (p. 7-8) “In the summer of 1811, the author was called to visit, professionally, Don Francisco de Salazar, who had arrived a few days before in London, on his route from Lima to Cadiz, as a Deputy to the Spanish Cortes. He informed him, that Vaccination had been practised with so much energy and success in Lima, that for the last twelve months there had occurred not only no death from, but no case of, Small Pox: that the new born children, of all ranks, are carried as regularly to the Vaccinating house as to the font of baptism; that the Small Pox is entirely extinguished all over Peru; nearly so in Chili; and that there has been no compulsory interference on the part of the government to promote Vaccination.”