Jaundice: Its Pathology and Treatment: With the Application of Physiological Chemistry to the Detection and Treatment of Diseases of the Liver and PancreasHarley, George
Science
Jaundice: Its Pathology and Treatment: With the Application of Physiological Chemistry to the Detection and Treatment of Diseases of the Liver and Pancreas
Harley, George
Jaundice
I had occasion to witness a good example of {27} this form of disease
in the person of a French gentleman, who was brought to me seven days
after his arrival in England, on account of his skin having assumed a
most intense yellow hue. It appeared that he had come to England on a
visit to some of his friends, and rather enjoying the novelty of an
English table, indulged too freely in a quantity and quality of food to
which he had hitherto been a stranger. The consequence was, that within
three days after his arrival he began to suffer from hepatic
tenderness, and dyspeptic symptoms; the skin at the same time assumed a
dusky hue, which soon merged into a decided yellowness. These symptoms
were accompanied by pipe-clay stools and saffron-coloured urine; on the
latter being tested it gave a distinct bile pigment, but no bile acid
reaction--a point which I shall afterwards have occasion to show, is of
a certain diagnostic value in obscure cases of jaundice. This
gentleman, under the influence of benzoic acid, perfectly recovered his
normal complexion in the short space of a week.
There is another form of jaundice from active congestion, viz., that
due to the presence of zymotic disease, such as ague, typhus, and other
fevers. As an illustration of this kind of affection, I shall cite one
arising from the first of these causes, namely, ague. And the best
example I {28} can give is one that has recently fallen under my
notice, and which occurred in the person of a member of our own
profession. The gentleman was for several years surgeon to one of our
large colonial hospitals, but in consequence of repeated attacks of
intermittent fever, was forced to resign the appointment, as well as a
lucrative practice, and return to England. He has now been at home for
two years, and although his general health has much improved, still
suffers from occasional attacks of his old enemy. On consulting me
regarding his case several months ago, he mentioned, that while
suffering from the above-named attacks, he occasionally suddenly passed
five or six ounces of urine as dark as chocolate, and this would recur
perhaps once in twenty-four hours, during two or three days, and then
as suddenly disappear. This urinary symptom being an unusual one, I
requested him to send me on the next occasion a specimen of the fluid.
In the beginning of last November[9] I received three samples of urine,
one passed at eight A.M., which was clear, pale, of a specific gravity
of 1025, of an acid reaction, deposited no lithates, and contained no
albumen, being in fact normal in every respect; another quantity passed
at two P.M., of {29} a chocolate brown colour, opaque, turbid, having a
specific gravity of 1032, of an acid reaction, depositing lithates,
containing albumen,[10] some sugar, and a large excess of urea (3·6 per
cent.) and urohæmatine; a third sample passed at night, of a specific
gravity of 1021, also with an acid reaction, depositing lithates in
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