Jaundice: Its Pathology and Treatment: With the Application of Physiological Chemistry to the Detection and Treatment of Diseases of the Liver and PancreasHarley, George
Science
Jaundice: Its Pathology and Treatment: With the Application of Physiological Chemistry to the Detection and Treatment of Diseases of the Liver and Pancreas
Harley, George
Jaundice
small quantity, but containing no albumen. The percentage of urea in
this urine was exactly one-half (namely, 1·8) of what it was in the
preceding specimen passed at two P.M.
[Footnote 9: This was written last year, and therefore refers to
November, 1861.]
[Footnote 10: When examined with the microscope, this specimen of urine
was found to contain a large quantity of nucleated epithelium, and
granular cells; free granules of a hæmatine colour, granular
tube-casts, and a quantity of mucus; while the morning and evening
urines were perfectly free of any such substances.]
The varying conditions of these three urines clearly pointed to intense
congestion of the chylopoietic viscera, of a transient and periodic
character. Suiting the practice to the theory, mercurials were taken by
this gentleman in order to remove the congestion of the chylopoietic
viscera, and with the most favourable results, for, as I afterwards
learned, the jaundice and other disagreeable symptoms soon disappeared.
_Jaundice the Result of Passive Congestion of the Liver._
In this case the congestion, instead of arising from an increased flow
of blood to the liver, as {30} in the preceding, is the result of some
cause impeding the outward flow of blood from the liver. Thus for
example, passive hepatic congestion may arise from valvular disease of
the heart, or from any pulmonary affection obstructing the circulation
of blood through the lungs (pneumonia, &c.). Jaundice from the passive
form of hepatic congestion, is not so common as jaundice from the
active form, in consequence of the former being, as a rule, much
slighter than the latter. Its pathology is, however, I believe, exactly
the same, viz. the result of the engorged hepatic capillaries
compressing the secreting cells and tubes, and thereby annulling their
functions. Such being the case, it is unnecessary for me to do more
than merely allude to this cause of jaundice.
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