Morton was a restless, energetic dentist, a rough man, resolute to get practice and make his fortune. Jackson was a quiet, scientific gentleman, unpractical and unselfish, in good repute as a chemist, geologist, and mineralogist. At the time of Wells's visit, Morton, who had been his pupil in 1842, and for a short time in 1843 his partner, was studying medicine and anatomy at the Massachusetts Medical College, and was living in Jackson's house. Neither Morton nor Jackson put much if any faith in Wells's story, and Morton witnessed his failure in the medical theatre. Still, Morton had it in his head that tooth-drawing might somehow be made painless, and even after Wells had retired from practice, he talked with him about it, and made some experiments, but, having no scientific skill or knowledge, they led to nothing. Still, he would not rest, and he was guided to success by Jackson, whom Wells advised him to ask to make some nitrous oxide gas for him. Jackson had long known, as many others had, of sulphuric ether being inhaled for amusement, and of its producing effects like those of nitrous oxide: he knew also of its employment as a remedy for the irritation caused by inhaling chlorine. He had himself used it for this purpose, and once, in 1842, while using it, he became completely insensible. He had thus been led to think that the pure ether might be used for the prevention of pain in surgical operations; he spoke of it with some scientific friends, and sometimes advised a trial of it; but he did not urge it or take any active steps to promote even the trial. One evening, Morton, who was now in practice as a dentist, called on him, full of some scheme which he did not divulge, and urgent for success in painless tooth-drawing. Jackson advised him to use the ether, and taught him how to use it. On that same evening, the 30th of September, 1846, Morton inhaled the ether, put himself to sleep, and, when he awoke, found that he had been asleep for eight minutes. Instantly, as he tells, he looked for an opportunity of giving it to a patient; and one just then coming in, a stout, healthy man, he induced him to inhale, made him quite insensible, and drew his tooth without his having the least consciousness of what was done. But the great step had yet to be made--the step which Wells would have tried to make if his test experiment had not failed. Clearly, operations as swift as that of tooth-drawing might be rendered painless, but could it be right to incur the risk of insensibility long enough and deep enough for a large surgical operation? It was generally believed that in such insensibility there was serious danger to life. Was it really so? Jackson advised Morton to ask Dr. J. C. Warren to let him try, and Warren dared to let him. It is hard now to think how bold the enterprise must have seemed to those who were capable of thinking accurately on the facts then known.