_November 18th._ The vein was more inflamed, and slight suppuration was visible at the orifice of the wound. Respiration 16; pulse 55. From this period to the 23rd, the pulse continued from 55 to 60, and the respiration varied from 12 to 18. _November 26th._ The swelling in the situation of the vein is rapidly subsiding; pulse 55; respiration 12. The animal gradually recovered, and on the 26th of February, 1849, was made the subject of another experiment. The right jugular vein having been opened, two fluid ounces of pure healthy pus were injected, and propelled in the course of the circulation, by pressure upon the vein externally. The vein became tense during the operation, and sensibly resisted the attempts that were made to propel its contents towards the heart. _Even forcible pressure was not sufficient to overcome the resistance offered to the return of blood._ Soon after the operation, the animal had a rigor; the breathing became laborious, but not accelerated; pulse 57. After the lapse of seven hours, the animal appeared dejected; he refused to eat or drink; the extremities were cold; breathing 16 in the minute; pulse 60, small and irregular. _February 27th._ The vein can be felt thickened as far as the sternum. The general symptoms are the same as on the previous evening. _28th._ There appears less constitutional irritation; pulse 60; respiration 14. _March 2nd._ Appetite still indifferent; pulse 60; respiration 16. From this date to the 7th, when the animal was destroyed, the general symptoms continued much the same, but the induration and swelling around the jugular vein, from the opening to the sternum, became greater. _Post-mortem appearances._ The left jugular vein was found completely obliterated. The remains of a firm coagulum obstructed its canal for some distance below the opening which had been made into it, and terminated, below, in an elongated conical portion, which adhered to one side only of the vessel. On the right side, an abscess had formed in the course of the vein; and for two inches, the whole of the parts were imbedded in a confused mass of pus and lymph, in which it was impossible to distinguish the structure of the vein. Both above and below this, for several inches, the vein was filled with coagula, which effectually obliterated it. These coagula extended for several inches in the course of the circulation; but beyond them, in both directions, the vessel was pervious. The lungs presented some slight spots of congestion, but not of the same characteristic kind observed in Experiment VI. The other organs were healthy. EXPERIMENT IX.[27] [27] This, and the following experiments, are among those recorded by M. Gaspard, referred to in the foregoing dissertation.