The Body at Work: A Treatise on the Principles of Physiology — John Shaqi
The Body at Work: A Treatise on the Principles of PhysiologyHill, Alex
Science
The Body at Work: A Treatise on the Principles of Physiology
Hill, Alex
Physiology
The thoracic duct provides for the overflow of lymph from the spaces
of the body. There is no circulation of lymph. Lymph from the liver
and from the intestines is constantly draining into the thoracic
duct, and thus returning to the blood-stream by a short direct route,
entering it without the necessity for reabsorption through the walls of
capillary vessels. By no means all of this fluid has exuded from the
blood-stream. Much of it is water which was poured into the stomach
as gastric juice, and into the intestines as the secretions of the
pancreas and other glands, or imbibed through the mouth and absorbed
by the lymphatics of the alimentary canal. The remainder of the water
taken up from the alimentary canal enters its bloodvessels. The diluted
blood flows to the liver, loaded with digested products which the
liver will store. As the blood parts with them the additional water
which has served for their transport exudes from the capillaries of
the liver into lymphatics, which empty it into the thoracic duct.
Large quantities of water are used in washing out digested products.
Secreted into the alimentary canal by the digestive glands, it passes
out through its wall as the vehicle of digested products. Collected
by lymphatic vessels, it is either carried directly into the thoracic
duct, or passed from lymph into blood, carried by blood to the liver,
again transferred from blood to lymph, and borne by the lymphatic
vessels of the liver to the thoracic duct.
Water exuded from blood into lymph may be reabsorbed into the blood
near the place where it was poured out, or it may reach the blood via
the thoracic duct. It would seem that the former is the natural, the
latter the emergency route; the former the course taken when an organ
is tranquil, the latter a necessity when the organ is active. If the
large lymphatic vessels of a limb are cut, no lymph escapes from them
so long as the limb is at rest. When the muscles contract lymph begins
to flow. If the limb is flexed and extended by hand, lymph flows. If
the muscles are squeezed or massaged, lymph flows. As the flow is set
up both by active contraction of the muscles and by passive movements
in which the muscles do not take part, it clearly must be due to
external pressure on the lymphatic vessels. As they are provided with
valves, squeezing them converts them into pumps. The fluid which they
contain is bound to go forwards. Additional fluid is squeezed into
them from the tissue-spaces. To a large extent, therefore, the outflow
of lymph from contracting muscles is to be explained as the result
of the pressure which the swelling muscles exert upon the lymphatic
vessels within their sheaths. But there is another factor which must
not be overlooked, although it cannot readily be estimated. When a
muscle is actively contracting its bloodvessels dilate. There is a
greater exudation of lymph; and reabsorption by blood is not equal to
the exudation.
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