CASE II.—A small Grunshi girl from Kumassi, about seven years of age, who had had yaws some time previously, felt pain in the nose a few months ago and noticed a small swelling on each side of the nose, and this gradually increased in size till it reached its present condition. Her mother was most anxious to have it removed on account of the deformity. On inspection there was found to be an oval swelling on each side of the nose, attached to the nasal bones and the nasal process of the superior maxilla. The long axis of the swelling was directed downwards and outwards—an inch in length and half an inch in breadth. The nasal cartilages were not affected and the interior of the nose was normal. The orbital cavity, the mouth, and the nasal ducts were quite unaffected. The skin over the swelling was normal and freely movable. The patient felt no pain in the tumor and she had never had any headache. The growths were removed by operation. It was very difficult to obtain definite history as to the time when this patient had had yaws and as to the time when the growth appeared, but as far as I could make out the yaws were well developed when the swelling was first noticed. _Moderately Developed Cases._—CASE III.—A young man, a Ga native, who had had yaws about seven years ago, felt pain in the nose and got a person to look into it, who said that there were yaw spots on the mucosa, and later a small swelling on each side of that organ was noticed. These small swellings grew slowly to their present size, and the patient said that they were still increasing. He complained of frontal headache and of slight pain in the swellings in wet weather. On inspection two symmetrically placed swellings were seen on each side of the nose, looking somewhat like small eggs. They were oval in shape, with the long axis directed downwards and outwards. The left measured two inches by two inches and the right three inches by two and a half inches. A profile view showed that they were slightly concave on the side towards the orbit. They did not affect the orbital or nasal cavities, nor did they project into the mouth or affect the nasal ducts or the cartilages of the nose. They were attached to the nasal bones, the nasal process of the superior maxilla, and to the superior maxilla itself. They were smooth, but on the left side the tumor rose to a central ridge. The skin over the swellings was quite normal and was freely movable. In order to see clearly, the patient often had to bend his head somewhat. The growths were removed by operation. CASE IV.—The patient was an Akwapim woman, aged about twenty years. This case was similar to Case III., but the swellings, which had started when the patient (who had suffered from yaws) was seven years of age, were rather more rounded. She would not consent to operation.