Let us now pass to the consideration of that special substance, or rather class of substances, whose properties form the chief subject of botany and of zoölogy, as truly as those of the silicates form the chief subject of mineralogy: I mean the life-slimes, or protoplasm. Let us begin by cataloguing the general characters of these slimes. They one and all exist in two states of aggregation, a solid or nearly solid state and a liquid or nearly liquid state; but they do not pass from the former to the latter by ordinary fusion. They are readily decomposed by heat, especially in the liquid state; nor will they bear any considerable degree of cold. All their vital actions take place at temperatures very little below the point of decomposition. This extreme instability is one of numerous facts which demonstrate the chemical complexity of protoplasm. Every chemist will agree that they are far more complicated than the albumens. Now, albumen is estimated to contain in each molecule about a thousand atoms; so that it is natural to suppose that the protoplasms contain several thousands. We know that while they are chiefly composed of oxygen, hydrogen, carbon, and nitrogen, a large number of other elements enter into living bodies in small proportions; and it is likely that most of these enter into the composition of protoplasms. Now, since the numbers of chemical varieties increase at an enormous rate with the number of atoms per molecule, so that there are certainly hundreds of thousands of substances whose molecules contain twenty atoms or fewer, we may well suppose that the number of protoplasmic substances runs into the billions or trillions. Professor Cayley has given a mathematical theory of “trees,” with a view of throwing a light upon such questions; and in that light the estimate of trillions (in the English sense) seems immoderately moderate. It is true that an opinion has been emitted, and defended among biologists, that there is but one kind of protoplasm; but the observations of biologists, themselves, have almost exploded that hypothesis, which from a chemical standpoint appears utterly incredible. The anticipation of the chemist would decidedly be that enough different chemical substances having protoplasmic characters might be formed to account, not only for the differences between nerve-slime and muscle-slime, between whale-slime and lion-slime, but also for those minuter pervasive variations which characterise different breeds and single individuals.