For a time I failed to look beyond the ailments of the stomach for curative results, until really surprising news began to reach me from many sources. There would come to me those who had to tell about clearer vision, acuter hearing, a stronger sense of smelling, etc., senses that were not thought to be affected by disease; or there would be news that chronic, local ailings, as nasal or bronchial catarrhs, skin diseases, hemorrhoids, or other intractable disease, in some mysterious manner, were undergoing a decline under the new regime. In the domain of drugs we have medicines that vivid imagination has endowed with presumed affinities for locations that are diseased. They enter the circulation and happily get off at the right spot, to act curatively; but no theories are advanced as to how they aid in the construction of new cells or atoms, or how they aid in the disposal of the old ones. Construction, destruction! There is no death of atoms: really nothing is generated, nothing destroyed: the change is but the rearranging of ultimate elements; and how is a drug to influence any more than would be in case of the affinities of chemistry? Hazy conceptions, crude means! The ultimate cell multiplies by division to become bone, nails, hair, ligaments, muscles, fat, the brain, the whole body. Where along the line in the reconstructive work called by a disease or injury is a medicine to apply with power to aid? In what way the need to be expressed, in what operative way the helpful assistance made clear, that faith without works that are seen can be made strong? The chemist never rushes into print with news that another element has been discovered until demonstrative evidence has placed the matter beyond all question. If anything new is discovered in the firmaments, adequate means to an end will be able to reveal it to all interested eyes. The impressions of science are quite different from the impressions of the materia medica; and the miracles of cure that are displayed by the column in even the highest class public prints are never in reach of scientific explanation. A new element is announced; we know instantly that it has been actually discovered. A new cure is announced; we instantly may know that the evidences will never be displayed along the lines of science. I now unfold a theory of my own of the origin and development of disease, and the development of cure, in which the physical changes involved in some of the processes are in reach of the microscope. It is my impression that, with rare exceptions, people are born with actual structural weaknesses, local or general, that may be called ancestral legacies. These are known as constitutional tendencies to disease.