DIRECTIONS FOR FILLING THIS BLANK.--Column A is to be left blank by the attending physician; column B contains the running number of the animal inoculated; C is to be recorded only in fitting cases; D, on the other hand, is never to be omitted; under E the fitting column is to be marked thus: “!”; in column F, IV, the degree of reaction following the inoculation is to be noted by signs, thus: O = Failure of any reaction whatsoever (R = O); I = short febrile reaction; II = 2-4 days of fever; III = 5-8 days of reaction associated with other disturbances of health (cough, loss of weight, diminution of appetite, diarrhœa, etc.). In the same manner the degree of the reaction to a later tuberculin test is to be recorded (column G). In column H the weight is always to be accompanied by the date. _The returns are to be made as soon as the data for about 100 cattle have been secured._ C. General report: This includes a report on the manner of keeping the inoculated cattle, the hygienic conditions of the stables, previous occurrence of _perlsucht_ in the cattle of the herd, previous use of other means of suppression of tuberculosis and their result, etc., etc. 4. The owners of the cattle must see to it that the inoculations are properly made and they themselves must bear all consequences resulting from defective inoculation. Drs. Siebert & Ziegenbein can in no way accept responsibility for this. * * * * * The preceding conditions are still adhered to in many large dairy farms. To a number of smaller dairies we have allowed easier conditions. An example is afforded in the following order of the Ministry of the Interior of the Grandduchy of Hesse. MINISTRY OF THE INTERIOR OF THE GRANDDUCHY OF HESSE, DEPARTMENT OF PUBLIC HEALTH. To the Grandducal County Veterinarians: Whereas, following the proclamation of the Ministry of the Interior dated Aug. 19, 1902, a large number of replies has been received from the farmers, it is ordered that the inoculations be hereafter made in accordance with the following principles: 1. The protective inoculation consists in the intravenous injection of a _single_ immunizing unit of tubercle germs (derived from man), rubbed up with sterile salt solution; and in a second intravenous injection, three months later, of _five_ immunizing units of the same germs. 2. The germs in question can be obtained in glass tubes containing 5 or 20 units. 3. As a rule only cattle without external manifestations of disease, aged from three weeks to four months (at the first inoculation) should be inoculated. With healthy animals of this age it is unnecessary to test them previously with tuberculin, even if they belong to a notoriously tubercular herd.