The great English authority, Daniel Hack Tuke, in his work, “The Influence of the Mind on the Body in Health and Disease,” quotes from Unzer’s work, published in Germany in the year 1771: “Expectation of the action of a remedy often causes us to experience its operation beforehand.” And John Hunter said as early as 1786: “I am confident that I can fix my attention to any part until I have a sensation in that part.” A great number of cases are recorded where complete insensibility to bodily pain has been induced without the use of drugs. The intention of administering a certain drug was made known in this manner. Bread pills have acted as decided cathartics, and an empty chloroform or ether bottle put the sensitive into a profound stupor or insensibility. Dr. Woodhouse Braine, of the Charing Cross Hospital, writes: “During the year 1862 I was called upon to give chloroform to a very nervous and highly hysterical girl, who was about to have two fatty tumors of the scalp removed. On going into the operating room, it was found that the bottle containing the chloroform had been removed to the dispensary, and on testing the Snow’s inhaler, which at that time I was in the habit of using, I found it to be quite devoid of even any smell of chloroform. Then, having sent for the bottle, in order to accustom the girl to the face-piece, I applied it to her face, and she at once began to breathe rapidly through it. When she had done this for about half a minute, she said, ‘Oh, I feel it, I feel I am going off,’ and as the chloroform bottle had not arrived, she was told to go on breathing quietly. At this time her hand, which had been resting across her chest, slipped down by her side, and as she did not replace it, I thought I would pinch her arm gently to see the amount of discomfort her hysterical state would induce her to bear. She did not notice a gentle pinch, and so I pinched her harder, and then as hard as I could, and to my surprise I found that she did not feel at all. Finding this was the case, I asked the operator to begin, and he incised one of the tumors, and then, as the cyst was only slightly adherent, peeled it away. At this time I had removed the face-piece, and, wishing to see the effect of her imagination, I said to the operator, who was going to remove the second tumor, ‘Wait a minute; she seems to be coming round.’ Instantly her respiration, which had been quite quiet, altered in character, becoming rapid as when I first applied the inhaler, and she commenced moving her arms about. I then replaced the face-piece, and her breathing again became quiet, and she submitted to the second operation without moving a muscle. When the water dressing and bandages were applied, in answer to the question as to whether she had felt anything, she said, ‘No; I was quite unconscious of all that was done.’” The mental phenomenon that we observe in this case clearly shows how completely the sensation of the patient was suspended by the